Bleier Blake J, Anna Shelley L, Walker Lynn M
Department of Chemical Engineering , Carnegie Mellon University , Pittsburgh , Pennsylvania 15213 , United States.
J Phys Chem B. 2018 Apr 12;122(14):4067-4076. doi: 10.1021/acs.jpcb.8b01013. Epub 2018 Mar 26.
The goal of this work is to develop a simple microfluidic approach to characterizing liquid-liquid phase behavior in complex aqueous mixtures of organics and salts. We take advantage of the permeability of inexpensive microfluidic devices to concentrate aqueous solutions on chip. We demonstrate a technique that allows phase boundaries to be identified with high compositional resolution and small sample volumes. Droplets of single phase samples are produced on-chip and concentrated in the device beyond the phase boundary line to map system phase behavior. Results are demonstrated on ammonium sulfate and organic (poly(ethylene oxide)) aqueous solutions and compared with macroscopic and literature results.
这项工作的目标是开发一种简单的微流控方法，用于表征有机物和盐的复杂水性混合物中的液-液相行为。我们利用廉价微流控装置的渗透性在芯片上浓缩水溶液。我们展示了一种技术，该技术能够以高成分分辨率和少量样品体积识别相界。在芯片上产生单相样品的液滴，并将其浓缩在装置中相界线之外，以绘制系统相行为。以硫酸铵和有机（聚环氧乙烷）水溶液为例展示了结果，并与宏观和文献结果进行了比较。
