利用生物传感器探索益生菌菌株降低细菌 SOS 反应和致突变性的潜力。
The Use of Biosensors to Explore the Potential of Probiotic Strains to Reduce the SOS Response and Mutagenesis in Bacteria.
机构信息
Academy of Biology and Biotechnologies, Southern Federal University, 344090 Rostov-on-Don, Russia.
出版信息
Biosensors (Basel). 2018 Mar 16;8(1):25. doi: 10.3390/bios8010025.
Abstract
A model system based on the MG1655 (pRecA-lux) Lux-biosensor was used to evaluate the ability of the fermentates of eight probiotic strains to reduce the SOS response stimulated by ciprofloxacin in bacteria and mutagenesis mediated by it. Preliminary attempts to estimate the chemical nature of active components of the fermentates were conducted.
摘要
采用基于 MG1655（pRecA-lux）Lux 生物传感器的模型系统，评估了 8 株益生菌菌株发酵产物降低环丙沙星刺激细菌中 SOS 反应和由其介导的突变的能力。还初步尝试评估发酵产物中活性成分的化学性质。
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