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上颈段脊髓刺激术作为三叉神经病变的一种替代治疗方法

Upper Cervical Spinal Cord Stimulation as an Alternative Treatment in Trigeminal Neuropathy.

作者信息

Velásquez Carlos, Tambirajoo Kantharuby, Franceschini Paulo, Eldridge Paul R, Farah Jibril Osman

机构信息

Department of Neurological Surgery and Spine Unit, Hospital Universitario Marqués de Valdecilla and Instituto de Investigación Marqués de Valdecilla (IDIVAL), Santander, Spain.

Department of Neurosurgery, The Walton Centre NHS Foundation Trust, Liverpool, United Kingdom.

出版信息

World Neurosurg. 2018 Jun;114:e641-e646. doi: 10.1016/j.wneu.2018.03.044. Epub 2018 Mar 14.

Abstract

OBJECTIVE

To describe the indications and outcomes of upper cervical cord stimulation in trigeminal neuropathy.

METHODS

A consecutive single-center series of patients was retrospectively reviewed. It included 12 patients with trigeminal neuropathy treated with upper cervical spinal cord stimulation. Clinical features, complications, and outcomes were reviewed.

RESULTS

All patients had a successful trial before the definitive implantation of a spinal cord stimulator at the level of the craniocervical junction. The mean follow-up period was 4.4 years (range, 0.3-21.1 years). The average coverage in the pain zone was 72% and the median baseline, trial, and postoperative numeric rating scale (NRS) was 7, 3, and 3, respectively. When compared with the baseline, the mean reduction achieved in the postoperative average numeric rating scale was 4 points, accounting for a 57.1% pain reduction. The long-term failure rate was 25%.

CONCLUSIONS

Despite there being enough evidence to consider upper cervical spinal cord stimulation as an effective treatment for patients with neuropathic trigeminal pain, a randomized controlled trial is needed to fully assess its indications and outcomes and compare it with other therapeutic approaches.

摘要

目的

描述三叉神经病变中上颈段脊髓刺激的适应症及疗效。

方法

对一个连续的单中心患者系列进行回顾性分析。该系列包括12例接受上颈段脊髓刺激治疗的三叉神经病变患者。对其临床特征、并发症及疗效进行分析。

结果

所有患者在颅颈交界水平最终植入脊髓刺激器之前试验均成功。平均随访期为4.4年(范围0.3 - 21.1年)。疼痛区域的平均覆盖范围为72%,基线、试验期及术后数字评分量表(NRS)的中位数分别为7、3和3。与基线相比,术后平均数字评分量表的平均降低值为4分,疼痛减轻57.1%。长期失败率为25%。

结论

尽管有足够证据将上颈段脊髓刺激视为治疗神经性三叉神经痛患者的有效方法,但仍需要进行随机对照试验以全面评估其适应症及疗效,并与其他治疗方法进行比较。

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