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电视胸腔镜肺叶切除术或肺段切除术的趋势与结果:一项国家外科质量改进项目分析

Trends and Outcomes of Thoracoscopic Lobectomy or Segmentectomy: A National Surgical Quality Improvement Project Analysis.

作者信息

Mehta Hemalkumar, Osasona Ayodele, Shan Yong, Goodwin James S, Okereke Ikenna C

机构信息

Department of Surgery, University of Texas Medical Branch, Galveston, Texas.

Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas.

出版信息

Semin Thorac Cardiovasc Surg. 2018;30(3):350-359. doi: 10.1053/j.semtcvs.2018.03.002. Epub 2018 Mar 13.

Abstract

Video-assisted thoracoscopic surgery may be associated with less morbidity than open lobectomy or segmentectomy, but some studies have questioned the benefit of thoracoscopic surgery. This study aimed to determine trends and factors associated with patient's likelihood of undergoing thoracoscopic lobectomy or segmentectomy and to compare outcomes with each approach. This retrospective study included adult patients undergoing pulmonary lobectomy or segmentectomy from the American College of Surgeons National Surgical Quality Improvement Project from 2007 to 2015 (n = 14,717). Logistic regression analysis was conducted to determine the association of patient demographics, clinical characteristics, and surgeon specialty with thoracoscopic lobectomy or segmentectomy. Propensity score matching was performed to evaluate outcomes for thoracoscopic and open lobectomy or segmentectomy. Use of thoracoscopic lobectomy or segmentectomy increased from 11.6% in 2007 to 60.6% in 2015 (P< 0.0001). Older patients, females, and Hispanics were more likely to undergo thoracoscopic lobectomy, whereas morbidly obese patients, patients with higher American Society of Anesthesiology class, and patients with 4-6 frailty conditions had a lower likelihood of receiving thoracoscopic lobectomy or segmentectomy. Thoracic surgeons had 57% (odds ratio 1.57, 95% confidence interval 1.36-1.81) higher odds of performing thoracoscopic surgery than other surgeons. Thoracoscopic lobectomy or segmentectomy reduced risk of 30-day mortality (1.0% vs 1.9%; odds ratio 0.51, 95% confidence interval 0.37-0.70) and resulted in shorter length of stay (4 days vs 6 days; Beta coefficient = -0.37, P < 0.0001), and fewer complications. The frequency of thoracoscopic lobectomy or segmentectomy has increased substantially over the last 10 years and now accounts for over half of lobectomies. Video-assisted thoracoscopic surgery showed better outcomes than open lobectomy or segmentectomy.

摘要

电视辅助胸腔镜手术的发病率可能低于开放性肺叶切除术或肺段切除术,但一些研究对胸腔镜手术的益处提出了质疑。本研究旨在确定与患者接受胸腔镜肺叶切除术或肺段切除术可能性相关的趋势和因素,并比较两种手术方式的结果。这项回顾性研究纳入了2007年至2015年美国外科医师学会国家外科质量改进项目中接受肺叶切除术或肺段切除术的成年患者(n = 14717)。进行逻辑回归分析以确定患者人口统计学、临床特征和外科医生专业与胸腔镜肺叶切除术或肺段切除术之间的关联。采用倾向得分匹配法评估胸腔镜和开放性肺叶切除术或肺段切除术的结果。胸腔镜肺叶切除术或肺段切除术的使用从2007年的11.6%增加到2015年的60.6%(P < 0.0001)。老年患者、女性和西班牙裔患者更有可能接受胸腔镜肺叶切除术,而病态肥胖患者、美国麻醉医师协会分级较高的患者以及有4至6种虚弱状况的患者接受胸腔镜肺叶切除术或肺段切除术的可能性较低。胸外科医生进行胸腔镜手术的几率比其他外科医生高57%(优势比1.57,95%置信区间1.36 - 1.81)。胸腔镜肺叶切除术或肺段切除术降低了30天死亡率(1.0%对1.9%;优势比0.51,95%置信区间0.37 - 0.70),缩短了住院时间(4天对6天;β系数 = -0.37,P < 0.0001),且并发症更少。在过去10年中,胸腔镜肺叶切除术或肺段切除术的频率大幅增加,现在占肺叶切除术的一半以上。电视辅助胸腔镜手术的结果优于开放性肺叶切除术或肺段切除术。

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