Nakao K, Morii N, Itoh H, Yamada T, Shiono S, Sugawara A, Saito Y, Mukoyama M, Arai H, Sakamoto M
Klin Wochenschr. 1987;65 Suppl 8:103-8.
Biologically active peptides isolated in the peripheral organs often distribute in the central nervous system and vice versa. Accumulating evidence supports the concept that the effects of centrally active peptides are often, although not always, complementary to their peripheral actions. Atrial natriuretic polypeptide (ANP) is one of these biologically active peptides. Evidence presented here indicates that ANP is involved in the cardiovascular control as a neuropeptide in the central nervous system as well as a circulating hormone in the periphery.
在外周器官中分离出的生物活性肽常常分布于中枢神经系统，反之亦然。越来越多的证据支持这样一种观点，即中枢活性肽的作用通常（尽管并非总是如此）与其外周作用互补。心房钠尿肽（ANP）就是这些生物活性肽之一。此处提供的证据表明，ANP作为中枢神经系统中的一种神经肽以及外周的一种循环激素参与心血管控制。
