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居住在约旦的患有糖尿病的巴勒斯坦难民的药物依从性:一项横断面研究。

Medication adherence by Palestine refugees living in Jordan who have diabetes: a cross-sectional study.

作者信息

Canali Giulia, Tittle Victoria, Seita Akihiro

机构信息

United Nations Relief and Works Agency for Palestine Refugees in the Near East (UNRWA), Amman, Jordan.

United Nations Relief and Works Agency for Palestine Refugees in the Near East (UNRWA), Amman, Jordan.

出版信息

Lancet. 2018 Feb 21;391 Suppl 2:S13. doi: 10.1016/S0140-6736(18)30379-9.

Abstract

BACKGROUND

The United Nations Relief and Works Agency for Palestine Refugees in the Near East (UNRWA) estimated that in 2016, 11% of Palestine refugees older than 40 years living in Jordan were diagnosed with diabetes and that the disease is controlled in only 45% of Palestine refugees with diabetes. As medication adherence is one of the most important modifiable self-care behaviours to achieve adequate metabolic control, the aims of this study were to measure medication adherence and to review the factors associated with different levels of medication adherence in patients with diabetes.

METHODS

This cross-sectional study was a survey of patients with type 1 and type 2 diabetes who attended medical care at the UNRWA Amman New Camp health centre in Jordan. Medication adherence was measured using the Morisky Medication Adherence Scale (MMAS-8), and results were used as outcome variable. Data on factors associated with adherence were collected using a pre-tested patient questionnaire and patients' electronic records, and these factors were used as explanatory variables. Logistic regression analysis of each explanatory variable against the outcome variable was done to estimate crude odds ratios. Data were analysed using STATA version 13.0.

FINDINGS

763 patients were included in the study. 557 (73%) patients did not adhere to their diabetes drug therapy. Univariate analysis showed that the factors associated with non-adherence were: the use of multiple providers for diabetes care (crude odds ratio 0·51, 95% CI 0·28-0·91) and diabetes drugs (0·22, 0·09-0·56); satisfaction with the quality of UNRWA's diabetes care (4·51, 1·05-19·45) and with the explanation of the disease and treatment presented by UNRWA's health professionals (2·72, 1·24-5·29); and trust in UNRWA's health staff (3·61, 1·4-9·32).

INTERPRETATION

Decreased odds of adherence was associated with the use of multiple providers of care and diabetes medication, whereas increased odds of adherence correlated with full satisfaction with the quality of care, explanation of the disease, and treatment and trust in UNRWA health-care staff. These findings show the importance of health-system-related factors in affecting adherence to drug therapy in a population of Palestinian refugees with diabetes who accessed UNRWA health care in Jordan.

FUNDING

UNRWA.

摘要

背景

联合国近东巴勒斯坦难民救济和工程处(近东救济工程处)估计,2016年,居住在约旦的40岁以上巴勒斯坦难民中有11%被诊断患有糖尿病,而在患有糖尿病的巴勒斯坦难民中,只有45%的患者病情得到控制。由于药物依从性是实现充分代谢控制的最重要的可改变自我护理行为之一,本研究的目的是测量药物依从性,并回顾糖尿病患者中与不同药物依从性水平相关的因素。

方法

这项横断面研究是对在约旦近东救济工程处安曼新营地健康中心接受医疗护理的1型和2型糖尿病患者进行的调查。使用Morisky药物依从性量表(MMAS-8)测量药物依从性,并将结果用作结果变量。使用预先测试的患者问卷和患者电子记录收集与依从性相关的因素数据,并将这些因素用作解释变量。针对结果变量对每个解释变量进行逻辑回归分析,以估计粗略比值比。使用STATA 13.0版本对数据进行分析。

结果

763名患者纳入研究。557名(73%)患者未坚持糖尿病药物治疗。单因素分析表明,与不依从相关的因素有:糖尿病护理使用多个提供者(粗略比值比0.51,95%置信区间0.28-0.91)和糖尿病药物(0.22,0.09-0.56);对近东救济工程处糖尿病护理质量的满意度(4.51,1.05-19.45)以及对近东救济工程处卫生专业人员提供的疾病和治疗解释的满意度(2.72,1.24-5.29);以及对近东救济工程处卫生工作人员的信任(3.61,1.4-9.32)。

解读

依从性降低与使用多个护理提供者和糖尿病药物有关,而依从性增加与对护理质量、疾病解释、治疗的完全满意以及对近东救济工程处医护人员的信任相关。这些发现表明,在约旦接受近东救济工程处医疗服务的巴勒斯坦糖尿病难民群体中,与卫生系统相关的因素在影响药物治疗依从性方面具有重要意义。

资助

近东救济工程处。

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