Gallois P, Pruvo J P
Presse Med. 1987 Jun 18;16(23):1151-3.
Nuclear magnetic resonance (NMR) and computerized tomography (CT) have become indispensable to the exploration of patients with vascular dementia. NMR is remarkable for its innocuity, its anatomical accuracy, its sensitivity and the three-dimensional approach it offers. CT is less sensitive, but the examinations are shorter and less costly. These two techniques seem to be about equally effective in visualizing multiple infarcts, although NMR gives a better contrast. In dementia due to multiple infarcts, the bilateral cortical and subcortical lesions coexist with moderate cortical trophy. The cerebral lacunae of lacunar dementia are better visualized by NMR; they are distributed on both sides, predominate in the frontal lobes and only produce slight cortical atrophy, less pronounced than ventricular dilatation. The main advantage of NMR is its high sensitivity in detecting early changes in the white matter, changes which are particularly perceptible in juxta- and periventricular areas in arteriosclerous subcortical leucoencephalopathy. NMR, not very specific here, does not readily separate these lesions from those of other types of leucoencephalopathy. The finding of hypodense areas at CT or of hypersignals at NMR (T2) around the ventricles may help in differentiating between vascular dementia, irrespective of its mechanism, and primary dementia.
核磁共振(NMR)和计算机断层扫描(CT)已成为血管性痴呆患者检查中不可或缺的手段。核磁共振以其无害性、解剖学准确性、敏感性以及提供的三维成像方法而著称。CT的敏感性较低,但检查时间较短且成本较低。这两种技术在显示多发性梗死方面似乎同样有效,尽管核磁共振的对比度更好。在多发性梗死所致的痴呆中,双侧皮质和皮质下病变与中度皮质萎缩并存。腔隙性痴呆的脑腔隙在核磁共振下显示得更好;它们双侧分布,以额叶为主,仅产生轻微的皮质萎缩,不如脑室扩张明显。核磁共振的主要优势在于其在检测白质早期变化方面具有高敏感性,这些变化在动脉硬化性皮质下白质脑病的脑室周围和脑室旁区域尤为明显。核磁共振在此处不太具有特异性,不容易将这些病变与其他类型的白质脑病病变区分开来。CT上脑室周围低密度区或核磁共振(T2)上高信号的发现可能有助于区分血管性痴呆(无论其机制如何)和原发性痴呆。