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通过左外侧开胸手术将左心室辅助装置植入并与降主动脉吻合。

Left ventricular assist device implantation with left lateral thoracotomy with anastomosis to the descending aorta.

作者信息

Ozbaran Mustafa, Yagdi Tahir, Engin Cagatay, Nalbantgil Sanem, Ozturk Pelin

机构信息

Department of Cardiovascular Surgery, Ege University Hospital, Izmir, Turkey.

Department of Cardiology, Ege University Hospital, Izmir, Turkey.

出版信息

Interact Cardiovasc Thorac Surg. 2018 Aug 1;27(2):186-190. doi: 10.1093/icvts/ivy061.

Abstract

OBJECTIVES

Standard implantation of the HeartWare left ventricular assist system is performed using the full sternotomy approach. However, successful implantation of left ventricular assist devices in patients with a previous median sternotomy, especially in high-risk patients, remains challenging. Herein, we compared the HeartWare left ventricular assist system implantation by thoracotomy with anastomosis of the outflow graft to the descending aorta with the standard sternotomy approach.

METHODS

Between March 2013 and June 2016, we implanted 118 adult patients with a HeartWare left ventricular assist system, excluding implants with concurrent procedures, paediatric cases and biventricular left ventricular assist device. Of these implants, 30 implants were performed with a lateral thoracotomy with outflow graft anastomosis to the descending aorta. The remaining implants were carried out with the standard median sternotomy with outflow graft anastomosis to the ascending aorta. Propensity matching using the variables age, body mass index, right atrial pressure, blood urea nitrogen, creatinine, cardiomyopathy type and Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) levels resulted in a comparative data set of 30 thoracotomy and 30 sternotomy patients.

RESULTS

Within the first 30 days, the incidence of right heart failure (17% vs 10%, thoracotomy vs sternotomy) and bleeding (10% vs 7%, respectively) were similar between the surgical approaches. Thirty-day survival was 93.3% for both groups. Currently, 3 patients in the thoracotomy cohort have been transplanted and 17 remain on support, while in the sternotomy cohort, 1 patient has been transplanted and 21 remain on support.

CONCLUSIONS

In our single-centre experience, the lateral thoracotomy with outflow graft anastomosis to the descending aorta had similar early outcomes compared to the standard sternotomy.

摘要

目的

HeartWare左心室辅助系统的标准植入采用全胸骨切开术。然而,在曾行正中胸骨切开术的患者中成功植入左心室辅助装置,尤其是高危患者,仍然具有挑战性。在此,我们比较了通过开胸手术将流出道移植物与降主动脉吻合植入HeartWare左心室辅助系统与标准胸骨切开术的方法。

方法

2013年3月至2016年6月期间,我们为118例成年患者植入了HeartWare左心室辅助系统,排除同期进行其他手术的植入病例、儿科病例和双心室左心室辅助装置。在这些植入手术中,30例采用左外侧开胸手术并将流出道移植物与降主动脉吻合。其余植入手术采用标准正中胸骨切开术并将流出道移植物与升主动脉吻合。使用年龄、体重指数、右心房压力、血尿素氮、肌酐、心肌病类型和机械辅助循环支持机构间注册中心(INTERMACS)分级等变量进行倾向匹配,得到了30例开胸手术患者和30例胸骨切开术患者的比较数据集。

结果

在术后30天内,两种手术方式的右心衰竭发生率(开胸手术组为17%,胸骨切开术组为10%)和出血发生率(分别为10%和7%)相似。两组的30天生存率均为93.3%。目前,开胸手术组有3例患者已接受移植,17例仍在接受支持治疗;而在胸骨切开术组,有1例患者已接受移植,21例仍在接受支持治疗。

结论

根据我们单中心的经验,与标准胸骨切开术相比,左外侧开胸手术并将流出道移植物与降主动脉吻合的早期效果相似。

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