Wünsch Z
Physiol Bohemoslov. 1987;36(2):111-8.
The Joint Model of the Contractile System of Muscle is a theoretical construction and the question is whether it may express adequately some aspects of the biological original. In addition to the previous results which presented preliminary calculations, simulation experiments have been performed with a dynamic version of the model. The relations found between the variables studied (length, shortening velocity, isotonic contraction load, shortening heat production rate and excess of effective activity), did not essentially differ from those established by preliminary calculations; the choice of appropriate parameter values and the introduction of some additional features in the system made it possible to obtain a better approximation of relations known from measurements on the biological object. The model discloses some relevant general aspects of the contractile system of "independent" generators of force and thus contributes to a specification of the relationships between molecular and macroscopic levels of contraction phenomena. Future development or correction of the concepts under consideration depend on more suitable empirical data and further simulation experiments.
肌肉收缩系统的联合模型是一种理论构建，问题在于它是否能充分表达生物原型的某些方面。除了之前给出初步计算结果外，还对该模型的动态版本进行了模拟实验。所研究变量（长度、缩短速度、等张收缩负荷、缩短热产生率和有效活动过量）之间发现的关系，与初步计算所确立的关系并无本质差异；选择合适的参数值并在系统中引入一些附加特征，使得能够更好地逼近从生物对象测量中得知的关系。该模型揭示了“独立”力发生器收缩系统的一些相关一般方面，从而有助于明确收缩现象分子水平和宏观水平之间的关系。所考虑概念的未来发展或修正取决于更合适的经验数据和进一步的模拟实验。
