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[孕期乙肝筛查]

[Hepatitis B screening in pregnancy].

作者信息

Vytiska-Binstorfer E, Schatten C, Huber J C, Reinold E

出版信息

Z Geburtshilfe Perinatol. 1987 Mar-Apr;191(2):68-70.

PMID:2955583
Abstract

At the I. Department of Obstetrics and Gynecology, University of Vienna, between April 1, 1985 and September 30, maternity patients between 24 and 28 weeks of gestation had their blood tested for hepatitis B. Out of 167 patients screened for hepatitis B, three had a positive hepatitis B surface antigen test (1.8%), nineteen a positive anti-hepatitis BsAg test. Two patients were positive for anti-hepatitis BeAg (1.2%), one was positive for hepatitis-BeAg (0.6%). The presence of hepatitis BeAg conveys a higher infant attack rate. Yet even in the absence of the antigen and/or the presence of anti-hepatitis BeAg, infection may lead to a fatal outcome. Also, if the mother is a carrier, risk of acquiring the infection because of chronic exposure is present. Therefore the question and possible need for routine Hepatitis B-screening during pregnancy arises, not only in maternity patients at high risk for hepatitis B.

摘要

1985年4月1日至9月30日期间,在维也纳大学第一妇产科,对妊娠24至28周的孕妇进行了乙肝血液检测。在167名接受乙肝筛查的患者中,3人乙肝表面抗原检测呈阳性(1.8%),19人抗乙肝表面抗原检测呈阳性。2名患者抗乙肝e抗原检测呈阳性(1.2%),1名患者乙肝e抗原检测呈阳性(0.6%)。乙肝e抗原的存在意味着婴儿感染率更高。然而,即使没有该抗原和/或存在抗乙肝e抗原,感染也可能导致致命后果。此外,如果母亲是携带者,由于长期接触,婴儿有感染的风险。因此,不仅在乙肝高危的产妇中,而且在所有孕妇中,都出现了孕期常规乙肝筛查的问题以及可能的需求。

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