Bastani Andisheh, Cofré Lizama L Eduardo, Zoghi Maryam, Blashki Grant, Davis Stephen, Kaye Andrew H, Khan Fary, Galea Mary P
1Department of Rehabilitation Medicine, Royal Melbourne Hospital, RMH-Royal Park Campus, 34-54 Poplar Rd Parkville, Melbourne, VIC 3052 Australia.
2Australian Rehabilitation Research Centre (ARRC), Royal Melbourne Hospital, Melbourne, Australia.
Cerebellum Ataxias. 2018 Mar 5;5:6. doi: 10.1186/s40673-018-0084-z. eCollection 2018.
Cranial-nerve non-invasive neuromodulation (CN-NINM) using the portable neuromodulation stimulator (PoNS™ device has been proposed as a novel adjuvant intervention to improve efficacy of gait and balance. This device modulates input and output signals during motor tasks which prompts neuroplastic changes. In this study, we investigated the efficacy of physiotherapy using the PoNS™ in a case with cerebellar degeneration.
The PoNS™ was used during a high-intensity physiotherapy programme delivered over 2 weeks (2 × 1.5 h sessions daily). Clinical and instrumented gait and balance tests were applied pre- and post-intervention.
The patient improved in all tests without any adverse effects.
This study showed the efficacy and feasibility of combined high-intensity physiotherapy and CN-NINM for gait and balance rehabilitation. Further studies should explore CN-NINM effects in larger and more diverse samples of neurological patients.
使用便携式神经调节刺激器（PoNS™ 设备）进行颅神经无创神经调节（CN-NINM）已被提议作为一种新型辅助干预措施，以提高步态和平衡的功效。该设备在运动任务期间调节输入和输出信号，从而促使神经可塑性变化。在本研究中，我们调查了在一名小脑变性患者中使用 PoNS™ 进行物理治疗的疗效。
在为期2周（每天2次，每次1.5小时）的高强度物理治疗方案中使用了 PoNS™。在干预前后进行了临床和仪器化的步态及平衡测试。
患者在所有测试中均有改善，且无任何不良反应。
本研究表明了高强度物理治疗与 CN-NINM 联合用于步态和平衡康复的疗效和可行性。进一步的研究应在更大且更多样化的神经疾病患者样本中探索 CN-NINM 的效果。
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