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脊髓刺激、轻度手术和再生医学:慢性疼痛的新型介入非阿片类治疗方法。

Spinal Cord Stimulation, MILD Procedure, and Regenerative Medicine, Novel Interventional Nonopioid Therapies in Chronic Pain.

机构信息

Department of Anesthesiology and Pain Medicine, LSU Health Science Center, Louisiana State University School of Medicine, 1542 Tulane Avenue, Room 659, New Orleans, LA, USA.

Beth Israel Deaconess Medical Center, Department of Anesthesiology, Critical Care and Pain Medicine, Harvard Medical School, Boston, MA, USA.

出版信息

Curr Pain Headache Rep. 2018 Mar 19;22(4):26. doi: 10.1007/s11916-018-0680-x.

DOI:10.1007/s11916-018-0680-x
PMID:29556832
Abstract

PURPOSE OF REVIEW

Chronic pain is a highly prevalent condition affecting millions of individuals.

RECENT FINDINGS

In recent years, newer treatments have emerged that are changing the way clinicians treat pain pathogenesis, including novel nonopioid strategies. In this regard, spinal cord stimulation, the MILD procedure, and regenerative medicine have shown promise. This review summarizes recent literature on these three emerging treatment strategies. The results of this review suggest that under certain conditions, spinal cord stimulation, the MILD procedure, and regenerative medicine can be effective treatment modalities.

摘要

目的综述

慢性疼痛是一种高发疾病,影响着数以百万计的个体。

最近的发现

近年来,出现了一些新的治疗方法,这些方法正在改变临床医生治疗疼痛发病机制的方式,包括新型非阿片类策略。在这方面,脊髓刺激、MILD 手术和再生医学显示出了希望。本综述总结了这三种新兴治疗策略的最新文献。本综述的结果表明,在某些情况下,脊髓刺激、MILD 手术和再生医学可以作为有效的治疗方式。

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1
Spinal Cord Stimulation, MILD Procedure, and Regenerative Medicine, Novel Interventional Nonopioid Therapies in Chronic Pain.脊髓刺激、轻度手术和再生医学:慢性疼痛的新型介入非阿片类治疗方法。
Curr Pain Headache Rep. 2018 Mar 19;22(4):26. doi: 10.1007/s11916-018-0680-x.
2
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引用本文的文献

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Emerging Novel Pharmacological Non-opioid Therapies in Headache Management: a Comprehensive Review.新兴的头痛管理中非阿片类药理学治疗方法:全面综述。
Curr Pain Headache Rep. 2019 Jul 8;23(8):53. doi: 10.1007/s11916-019-0808-7.

本文引用的文献

1
New advancements in spinal cord stimulation for chronic pain management.脊髓刺激在慢性疼痛管理中的新进展。
Curr Opin Anaesthesiol. 2017 Dec;30(6):710-717. doi: 10.1097/ACO.0000000000000531.
2
Efficacy of Platelet-Rich Plasma in Retarding Intervertebral Disc Degeneration: A Meta-Analysis of Animal Studies.富血小板血浆延缓椎间盘退变的疗效:动物研究的荟萃分析
Biomed Res Int. 2017;2017:7919201. doi: 10.1155/2017/7919201. Epub 2017 Jul 2.
3
Clinical Evidence for Spinal Cord Stimulation for Failed Back Surgery Syndrome (FBSS): Systematic Review.
脊髓刺激治疗失败性腰椎手术综合征(FBSS)的临床证据:系统评价。
Spine (Phila Pa 1976). 2017 Jul 15;42 Suppl 14:S61-S66. doi: 10.1097/BRS.0000000000002213.
4
Magnetic Resonance Imaging Evaluation of the Effects of Surgical Invasiveness on Paravertebral Muscles After Muscle-preserving Interlaminar Decompression (MILD).保留肌肉的椎板间减压术(MILD)后手术侵袭性对椎旁肌影响的磁共振成像评估
Clin Spine Surg. 2017 Mar;30(2):E76-E82. doi: 10.1097/BSD.0b013e31829eb9de.
5
MILD® Is an Effective Treatment for Lumbar Spinal Stenosis with Neurogenic Claudication: MiDAS ENCORE Randomized Controlled Trial.MILD®是治疗神经源性间歇性跛行型腰椎管狭窄症的有效方法:MiDAS ENCORE随机对照试验。
Pain Physician. 2016 May;19(4):229-42.
6
MiDAS ENCORE: Randomized Controlled Clinical Trial Report of 6-Month Results.MiDAS ENCORE:6个月结果的随机对照临床试验报告
Pain Physician. 2016 Feb;19(2):25-38.
7
Short-term outcomes of platelet-rich plasma injection for treatment of osteoarthritis of the knee.富血小板血浆注射治疗膝关节骨关节炎的短期疗效
Knee Surg Sports Traumatol Arthrosc. 2016 May;24(5):1665-77. doi: 10.1007/s00167-015-3784-4. Epub 2015 Sep 19.
8
Microsurgical decompression for central lumbar spinal stenosis: a single-center observational study.
Acta Neurochir (Wien). 2015 Jul;157(7):1165-71. doi: 10.1007/s00701-015-2450-4. Epub 2015 May 23.
9
Adult stem cell as new advanced therapy for experimental neuropathic pain treatment.成体干细胞作为实验性神经性疼痛治疗的新型先进疗法。
Biomed Res Int. 2014;2014:470983. doi: 10.1155/2014/470983. Epub 2014 Aug 13.
10
Modeling effects of spinal cord stimulation on wide-dynamic range dorsal horn neurons: influence of stimulation frequency and GABAergic inhibition.脊髓刺激对广动力范围背角神经元的建模效应:刺激频率和GABA能抑制的影响
J Neurophysiol. 2014 Aug 1;112(3):552-67. doi: 10.1152/jn.00254.2014. Epub 2014 Apr 30.