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头痛管理中的新型介入性非阿片类疗法。

Novel Interventional Nonopioid Therapies in Headache Management.

机构信息

Department of Anesthesiology, Critical Care, and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

Department of Anesthesiology, Perioperative Medicine and Pain Management, University of Miami School of Medicine, Jackson Memorial Hospital, Miami, FL, USA.

出版信息

Curr Pain Headache Rep. 2018 Mar 19;22(4):29. doi: 10.1007/s11916-018-0681-9.

Abstract

PURPOSE OF REVIEW

Headaches encompass a broad-based category of a symptom of pain in the region of the head or neck. For those patients who unfortunately do not obtain relief from conservative treatment, interventional techniques have been developed and are continuing to be refined in an attempt to treat this subset of patients with the goal of return of daily activities. This investigation reviews various categories of headaches, their pathophysiology, and types of interventional treatments currently available.

RECENT FINDINGS

Injection of botulinum toxin has been shown to increase the number of headache free days for patients suffering from chronic tension-type headaches. Suboccipital steroid injection has been demonstrated as a successful treatment option for patients suffering from cluster headache. Occipital nerve stimulation (ONS) has been described as a treatment for all types of trigeminal autonomic cephalgias. Percutaneous ONS is a minimally invasive and reversible approach to manage occipital neuralgia performed utilizing subcutaneous electrodes placed superficial to the cervical muscular fascia in the suboccipital area. Radiofrequency lesioning is another commonly used treatment in the management of chronic pain syndromes of the head and neck. If a diagnostic sphenopalatine ganglion block successfully resolves the patient's symptoms, neurolysis can be employed as a more permanent solution. Although many patients who suffer from headaches can be treated with conservative, less-invasive treatments, there still remains at present an ever-increasing need for those patients who are refractory to conservative measures and thus require interventional treatments. These procedures are continually evolving to become safer, more precise, and more readily available for clinicians to provide to their patients.

摘要

目的综述

头痛是头部或颈部区域疼痛症状的广泛类别。对于那些不幸无法通过保守治疗缓解的患者,已经开发出介入技术,并在不断完善,试图治疗这部分患者,目标是恢复日常活动。本研究综述了各种类型的头痛、其病理生理学以及目前可用的介入治疗类型。

最近的发现

肉毒毒素注射已被证明可增加慢性紧张型头痛患者无头痛天数。枕下类固醇注射已被证明是治疗丛集性头痛患者的有效治疗选择。枕神经刺激(ONS)已被描述为治疗所有类型的三叉神经自主头痛的方法。经皮 ONS 是一种微创和可逆的方法,用于管理枕神经痛,使用放置在颈肌筋膜下的皮下电极在枕下区域进行。射频消融是管理头颈部慢性疼痛综合征的另一种常用治疗方法。如果蝶腭神经节阻滞诊断性治疗成功缓解了患者的症状,可以采用神经松解术作为更持久的解决方案。尽管许多头痛患者可以通过保守、微创治疗,但目前仍有越来越多的患者对保守治疗措施无效,因此需要介入治疗。这些手术不断发展,变得更安全、更精确,更便于临床医生为患者提供。

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