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一项关于印度半城市人口中慢性阻塞性肺疾病患者抑郁症患病率及抑郁严重程度的研究。

A study on the prevalence of depression and the severity of depression in patients of chronic obstructive pulmonary disease in a semi-urban Indian population.

作者信息

Agarwal Abhishekl, Batra Sakshi, Prasad Rajendra, Verma Anand, Jilani Abdul Q, Kant Surya

机构信息

Era's Lucknow Medical College and Hospital, Department of Pulmonary Medicine.

出版信息

Monaldi Arch Chest Dis. 2018 Mar 19;88(1):902. doi: 10.4081/monaldi.2018.902.

DOI:10.4081/monaldi.2018.902
PMID:29557571
Abstract

Chronic obstructive pulmonary disease (COPD) is one of the few respiratory diseases which is associated with a number of comorbidities. Psychiatric disease like depression is a very important comorbidity of COPD because it decreases the feeling of wellbeing in the patient and also interferes with the compliance with medication thereby increasing the risk of hospitalization in the COPD patient. A cross-sectional study was done for two years in the department of pulmonary medicine at Era's Lucknow medical college and hospital, Lucknow. A total of 150 patients were enrolled for the study after a clinico-radiological screening for the diagnosis confirmed on spirometry. After the confirmation of the diagnosis of COPD in these patients, they were screened for depression using the PHQ-9 scale in our department of pulmonary medicine. The confirmation of the diagnosis of depression was done according to the ICD-10 guidelines for depression and the severity of depression was graded using HAM-D scale in the department of psychiatry at our institute. The most common age group enrolled in the study was 51-60 years of age (40.67%). One hundred and fifteen patients (76.7%) of the enrolled patients were smokers while the remaining 35 patients (23.3%) were non-smokers. Depression was found to be present in 46 out of the total 150 patients in the study. Thus, the prevalence of depression in our study was 30.67%. Depression was seen in COPD groups B,C and D. Out of the 46 patients of COPD with depression,18 had mild depression (39.13%), 26 had moderate depression (56.52%) and 2 had severe depression (4.35%). Hence, depression of all grades (i.e., mild, moderate and severe depression) is seen in COPD groups B, C and D.

摘要

慢性阻塞性肺疾病(COPD)是少数与多种合并症相关的呼吸系统疾病之一。像抑郁症这样的精神疾病是COPD非常重要的合并症,因为它会降低患者的幸福感,还会干扰患者对药物治疗的依从性,从而增加COPD患者住院的风险。在勒克瑙埃拉医学院和医院的肺病科进行了一项为期两年的横断面研究。在通过临床放射学筛查并经肺功能测定确诊后,共有150名患者纳入该研究。在这些患者确诊为COPD后,在我们的肺病科使用PHQ - 9量表对他们进行抑郁症筛查。根据国际疾病分类第10版(ICD - 10)抑郁症指南确诊抑郁症,并在我们研究所的精神科使用汉密尔顿抑郁量表(HAM - D)对抑郁症的严重程度进行分级。该研究纳入的最常见年龄组为51 - 60岁(40.67%)。纳入研究的患者中有115名(76.7%)是吸烟者,其余35名患者(23.3%)是非吸烟者。在该研究的150名患者中,共发现46名患有抑郁症。因此,我们研究中抑郁症的患病率为30.67%。在COPD的B、C和D组中均发现有抑郁症。在46名患有抑郁症的COPD患者中,18名患有轻度抑郁症(39.13%),26名患有中度抑郁症(56.52%),2名患有重度抑郁症(4.35%)。因此,在COPD的B、C和D组中均可见到各级抑郁症(即轻度、中度和重度抑郁症)。

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