Piccoli Giorgina B, Liu Zhi-Hong, Levin Adeera
Department of Clinical and Biological Sciences, University of Torino, Italy.
Nephrology, Centre Hospitalier Le Mans, Le Mans, France.
Arch Argent Pediatr. 2018 Apr 1;116(2):e273-e278. doi: 10.5546/aap.2018.eng.e273.
Chronic Kidney Disease affects approximately 10% of the world's adult population: it is within the top 20 causes of death worldwide, and its impact on patients and their families can be devastating. World Kidney Day and International Women's Day in 2018 coincide, thus offering an opportunity to reflect on the importance of women's health and specifically their kidney health, on the community, and the next generations, as well as to strive to be more curious about the unique aspects of kidney disease in women so that we may apply those learnings more broadly. Girls and women, who make up approximately 50% of the world's population, are important contributors to society and their families. Gender differences continue to exist around the world in access to education, medical care, and participation in clinical studies. Pregnancy is a unique state for women, offering an opportunity for diagnosis of kidney disease, but also a state where acute and chronic kidney diseases may manifest, and which may impact future generations with respect to kidney health. There are various autoimmune and other conditions that are more likely to impact women with profound consequences for child bearing, and on the fetus. Women have different complications on dialysis than men, and are more likely to be donors than recipients of kidney transplants. In this editorial, we focus on what we do and do not know about women, kidney health, and kidney disease, and what we might learn in the future to improve outcomes worldwide.
慢性肾脏病影响着全球约10%的成年人口：它位列全球前20大致死原因之内，对患者及其家庭的影响可能是毁灭性的。2018年世界肾脏日与国际妇女节重合，从而提供了一个契机，让我们思考女性健康尤其是她们的肾脏健康对社区及后代的重要性，同时努力对女性肾脏疾病的独特方面保持更多好奇，以便我们能更广泛地应用这些认知。女孩和女性约占全球人口的50%，她们是社会及其家庭的重要贡献者。在接受教育、获得医疗保健以及参与临床研究方面，全球范围内的性别差异依然存在。怀孕对女性来说是一种独特的状态，它既为诊断肾脏疾病提供了机会，但也是急性和慢性肾脏疾病可能显现的状态，并且可能在肾脏健康方面影响后代。有多种自身免疫性疾病和其他病症更有可能影响女性，对生育以及胎儿产生深远影响。女性在透析时出现的并发症与男性不同，而且她们成为肾脏移植供体的可能性大于受体。在这篇社论中，我们聚焦于我们对女性、肾脏健康和肾脏疾病已知和未知的方面，以及我们未来可能学到的有助于改善全球治疗效果的内容。
