Aldayel Abdulrahman Yousef, Alharbi Muteb Mousa, Shadid Asem Mustafa, Zevallos Juan Carlos
College of Medicine, Al Imam Mohammad Ibn Saud Islamic University, Riyadh, Saudi Arabia.
Department of Medical and Population Health Sciences Research, Herbert Wertheim College of Medicine, Florida International University, Miami, FL, United States.
Electron Physician. 2017 Dec 25;9(12):5871-5876. doi: 10.19082/5871. eCollection 2017 Dec.
Worldwide, stroke is considered the second leading cause of death, accounting for 11.8% of all deaths in 2013. In the Unites States (US), approximately 795,000 people have a stroke every year. Stroke has many different risk factors that vary by race/ethnicity. There is limited contemporary published literature about the prevalence of stroke among racial/ethnic groups in the US adult population.
This study aimed to determine the association between race/ethnicity and the prevalence of stroke among US adults in 2015.
This study was an observational, non-concurrent prospective of the Behavioural Risk Factor Surveillance System (BRFSS) in 2015 to assess the association between race/ethnicity and the prevalence of stroke. The final study sample was 432,814 US adults ≥ 18 years old. Variables were excluded from the model if there were missing, refused, or did not know responses to the variables of interest. A binary logistic regression analysis was used to obtain odds ratios (OR) and 95% confidence intervals (CI) for the association between race/ethnicity and stroke. The Chi-square test was used to study bivariate associations between categorical variables. The collinearity was assessed. A p-value of <0.05 was considered statistically significant. Statistical analysis was completed using STATA version 14 (Stata Corp, College Station, TX).
The highest proportion of participants (43%) were ≥ 44 years old with a balanced distribution of males and females. The highest proportion of stroke was found among Hispanics (4.2%) and non-Hispanic Blacks (4.1%) as compared to 3.2% among non-Hispanic Whites (p<0.001). Furthermore, Hispanics and Blacks were significantly more likely to develop stroke (OR=1.57, 95% CI=1.28-1.91; and OR=1.30, 95% CI=1.16-1.45, respectively) after adjusting for confounding variables.
Hispanics and Blacks had a higher prevalence of stroke in comparison with non-Hispanic Whites. Further studies are needed to verify these findings and to determine which factors may influence the stroke differences among these racial/ethnic groups.
在全球范围内,中风被认为是第二大致死原因,在2013年占所有死亡人数的11.8%。在美国,每年约有79.5万人中风。中风有许多不同的风险因素,因种族/民族而异。关于美国成年人口中不同种族/民族中风患病率的当代已发表文献有限。
本研究旨在确定2015年美国成年人中种族/民族与中风患病率之间的关联。
本研究是对2015年行为危险因素监测系统(BRFSS)进行的一项观察性、非同期前瞻性研究,以评估种族/民族与中风患病率之间的关联。最终研究样本为432,814名18岁及以上的美国成年人。如果对感兴趣的变量存在缺失、拒绝回答或不知道答案的情况,则将这些变量从模型中排除。采用二元逻辑回归分析来获得种族/民族与中风之间关联的比值比(OR)和95%置信区间(CI)。采用卡方检验研究分类变量之间的双变量关联。评估了共线性。p值<0.05被认为具有统计学意义。使用STATA 14版本(Stata公司,德克萨斯州大学站)完成统计分析。
参与者中比例最高的(43%)年龄≥44岁,男女分布均衡。与非西班牙裔白人中的3.2%相比,西班牙裔(4.2%)和非西班牙裔黑人(4.1%)中风比例最高(p<0.001)。此外,在调整混杂变量后,西班牙裔和黑人患中风的可能性显著更高(分别为OR=1.57,95%CI=1.28 - 1.91;OR=1.30,95%CI=1.16 - 1.45)。
与非西班牙裔白人相比,西班牙裔和黑人中风患病率更高。需要进一步研究来验证这些发现,并确定哪些因素可能影响这些种族/民族群体之间的中风差异。