Rapp Stephen R, Barnard Ryan T, Sink Kaycee M, Chamberlain Dana G, Wilson Valerie, Lu Lingyi, Ip Edward H
Department of Psychiatry and Behavioral Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Alzheimers Dement (Amst). 2018 Feb 23;10:237-244. doi: 10.1016/j.dadm.2018.01.008. eCollection 2018.
Aim is to evaluate validity, reliability, diagnostic precision, and user acceptability of computer simulations of cognitively demanding tasks when administered to older adults with and without cognitive impairment.
Five simulation modules were administered to 161 individuals aged ≥60 years with no cognitive impairment (N = 81), mild cognitive impairment (N = 52), or dementia (N = 28). Groups were compared on total accuracy and time to complete the tasks (seconds). Receiver operating characteristics were evaluated. Reliability was assessed over one month. Participants rated face validity and acceptability.
Total accuracy ( < .0001) and time ( = .0015) differed between groups. Test-retest correlations were excellent (0.79 and 0.88, respectively). Area under the curve ranged from good (0.77) to excellent (0.97). User ratings supported their face validity and acceptability.
Brief computer simulations can be useful in assessing cognitive functional abilities of older adults and distinguishing varying degrees of impairment.
目的是评估对有和没有认知障碍的老年人进行认知要求较高任务的计算机模拟时的有效性、可靠性、诊断准确性和用户可接受性。
对161名年龄≥60岁的个体进行了五个模拟模块测试，这些个体无认知障碍（N = 81）、轻度认知障碍（N = 52）或痴呆（N = 28）。比较了各组在总准确性和完成任务时间（秒）方面的差异。评估了受试者工作特征曲线。在一个月内评估了可靠性。参与者对表面效度和可接受性进行了评分。
各组之间的总准确性（<0.0001）和时间（=0.0015）存在差异。重测相关性极佳（分别为0.79和0.88）。曲线下面积从良好（0.77）到极佳（0.97）不等。用户评分支持其表面效度和可接受性。
简短的计算机模拟可用于评估老年人的认知功能能力并区分不同程度的损伤。
