Cho M M, Han P M, Thein M
Hum Nutr Clin Nutr. 1987 May;41(3):209-13.
Sixty-six children with satisfactory growth and 73 with unsatisfactory growth (both sexes) from three different age groups (1 year, 5 years and 10 years) were included in this study. It was observed that the serum concentrations of human growth hormone (hGH) in children with satisfactory growth ranged from 1.00 to 4.00 ng/ml and never exceeded 4.00 ng/ml. In a comparative study there was a significant increase in serum hGH levels in subjects of all age groups who were not growing satisfactorily. Twelve children between 12 and 13 months of age with unsatisfactory growth were nutritionally rehabilitated for 4 months and the changes in weight and serum hGH levels were assessed monthly. The results indicated a definite fall of hGH level after rehabilitation and reached the normal level 3 months after rehabilitation. Moreover, an inverse relationship between body weight and serum hGH level was observed.
本研究纳入了来自三个不同年龄组（1岁、5岁和10岁）的66名生长良好的儿童和73名生长不佳的儿童（包括男童和女童）。观察发现，生长良好的儿童血清人生长激素（hGH）浓度在1.00至4.00 ng/ml之间，且从未超过4.00 ng/ml。在一项对比研究中，所有生长不佳的各年龄组受试者血清hGH水平均显著升高。对12名12至13个月大、生长不佳的儿童进行了4个月的营养康复治疗，并每月评估体重和血清hGH水平的变化。结果表明，康复治疗后hGH水平明显下降，并在康复3个月后达到正常水平。此外，还观察到体重与血清hGH水平呈负相关。
