Neurosciences Research Center, Shiraz Medical School, Shiraz University of Medical Sciences, Shiraz, Iran; Jefferson Comprehensive Epilepsy Center, Department of Neurology, Thomas Jefferson University, Philadelphia, USA.
Neuropsychiatric Department, Aichi Medical University, Nagakute, Aichi, Japan.
Seizure. 2018 Apr;57:45-49. doi: 10.1016/j.seizure.2018.03.012. Epub 2018 Mar 12.
The purpose of this review was to investigate the prevalence of depression in people with epilepsy (PWE) in different countries in Asia.
We searched the electronic database PubMed on June 13, 2017 for articles in English that included the following search terms: "epilepsy" AND "depression" AND "country name" for all Asian countries since 1947. Relevant original studies from Asia were included if they reported the prevalence of depression in PWE. Papers studying special populations (e.g., elderly, veterans, etc.) were not included. In addition, experts in epilepsy field were invited from some Asian countries for an in-depth assessment.
Six hundred eighty-seven papers were reviewed and 26 related studies were included in this study. Depression is highly prevalent in PWE in different countries in Asia and the prevalence rates are consistent with rates reported in the literature from other countries: overall, about 25% of PWE suffer from depression.
In Asian countries, as elsewhere, depression is common in PWE. High quality data is scarce in many countries and validated screening tools [e.g., Neurological Disorders Depression Inventory for Epilepsy (NDDI-E)] to appropriately investigate the prevalence of depression in PWE are still lacking in many languages. Considering the high prevalence of depression among PWE, routine and periodic screening of all PWE for early detection and appropriate management of depression would be a reasonable approach.
本综述旨在调查亚洲不同国家癫痫患者（PWE）中抑郁的流行情况。
我们于 2017 年 6 月 13 日在电子数据库 PubMed 上以英文搜索了自 1947 年以来所有亚洲国家的以下检索词：“癫痫”和“抑郁”和“国家名称”。如果报告了 PWE 中抑郁的流行情况，则纳入包含这些搜索词的亚洲相关原始研究。不包括研究特殊人群（如老年人、退伍军人等）的论文。此外，还邀请了一些亚洲国家的癫痫领域专家进行深入评估。
共审查了 687 篇论文，其中 26 项相关研究纳入本研究。亚洲不同国家的 PWE 中抑郁发生率很高，且与其他国家文献报道的发生率一致：总体而言，约 25%的 PWE 患有抑郁。
在亚洲国家，与其他国家一样，PWE 中抑郁很常见。许多国家缺乏高质量数据，且许多语言中仍缺乏适当评估 PWE 中抑郁流行情况的经过验证的筛查工具[例如，癫痫患者的神经障碍抑郁量表（NDDI-E）]。考虑到 PWE 中抑郁的高发生率，对所有 PWE 进行常规和定期筛查，以早期发现和适当管理抑郁，可能是合理的方法。
