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经治疗与未经治疗的阻塞性睡眠呼吸暂停与抑郁症之间的关联

The Association between Treated and Untreated Obstructive Sleep Apnea and Depression.

作者信息

Haddock Nicole, Wells Mary Ellen

机构信息

a Department of Kinesiology University of North Carolina at Charlotte , Charlotte , North Carolina.

b Department of Allied Health Sciences University of North Carolina at Chapel Hill , Chapel Hill , North Carolina.

出版信息

Neurodiagn J. 2018;58(1):30-39. doi: 10.1080/21646821.2018.1428462.

Abstract

STUDY OBJECTIVES

The aims of this study were (1) to determine the association between obstructive sleep apnea (OSA) and depression and (2) to identify if treated or untreated OSA affects depression levels, in a sample of 51 patients.

METHODS

Participants were 18 years old or older, who were diagnosed with some form of OSA. A survey was administered at a local sleep clinic and via social media, Facebook. A Patient Health Questionnaire Depression Scale (PHQ-8) was used to assess depression.

RESULTS

Overall, 51 participants met the requirements and completed the survey. Participants who were currently not being treated for their OSA had a mean depression score of 18.9 (moderate-severe). In treated mild OSA participants, the mean depression score was 8; in participants with moderate OSA, the mean depression score was 13.7; and in patients with severe OSA, the mean depression score was 13.4. In untreated mild OSA participants, themean depression score was 15.3; in moderate OSA participants, the mean depression score was 17.3; and in severe OSA participants, the mean depression score was 18.4. A two-sided t test (P < 0.05) showed that participants with untreated sleep apnea have significantly higher depression scores than those with treated sleep apnea. Data also showed a higher average depression score among females with untreated OSA (17.3) versus males with untreated OSA (16.7).

CONCLUSIONS

The results showed an increase in depression levels among individuals with untreated OSA, lower depression scores in all levels of severity within treated OSA participants, and females had higher depression levels than men, in both treated and untreated OSA. These data could be useful in the future for physicians when assessing patients for sleep apnea or depression.

摘要

研究目的

本研究的目的是(1)确定阻塞性睡眠呼吸暂停(OSA)与抑郁症之间的关联,以及(2)在51名患者的样本中,确定接受治疗或未接受治疗的OSA是否会影响抑郁水平。

方法

参与者年龄在18岁及以上,被诊断患有某种形式的OSA。在当地睡眠诊所并通过社交媒体脸书进行了一项调查。使用患者健康问卷抑郁量表(PHQ-8)来评估抑郁情况。

结果

总体而言,51名参与者符合要求并完成了调查。目前未接受OSA治疗的参与者的平均抑郁评分为18.9(中度至重度)。在接受治疗的轻度OSA参与者中,平均抑郁评分为8;在中度OSA参与者中,平均抑郁评分为13.7;在重度OSA患者中,平均抑郁评分为13.4。在未接受治疗的轻度OSA参与者中,平均抑郁评分为15.3;在中度OSA参与者中,平均抑郁评分为17.3;在重度OSA参与者中,平均抑郁评分为18.4。双侧t检验(P < 0.05)表明,未接受治疗的睡眠呼吸暂停参与者的抑郁评分显著高于接受治疗的睡眠呼吸暂停参与者。数据还显示,未接受治疗的OSA女性的平均抑郁评分(17.3)高于未接受治疗的OSA男性(16.7)。

结论

结果显示,未接受治疗的OSA个体的抑郁水平升高,接受治疗的OSA参与者在所有严重程度水平下的抑郁评分较低,并且在接受治疗和未接受治疗的OSA中,女性的抑郁水平均高于男性。这些数据未来可能对医生评估睡眠呼吸暂停或抑郁症患者有用。

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