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Tamoxifen and ERα36: Fertilizing the seeds of breast cancer metastasis.

作者信息

Burness Monika L, Wicha Max S

机构信息

University of Michigan Comprehensive Cancer Center, Michigan Medicine, Ann Arbor, MI, USA.

出版信息

Cell Res. 2018 Apr;28(4):391-392. doi: 10.1038/s41422-018-0028-4.

DOI:10.1038/s41422-018-0028-4
PMID:29563540
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5939042/
Abstract
摘要

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Tamoxifen and ERα36: Fertilizing the seeds of breast cancer metastasis.他莫昔芬与雌激素受体α36:为乳腺癌转移播下种子
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Tamoxifen enhances stemness and promotes metastasis of ERα36 breast cancer by upregulating ALDH1A1 in cancer cells.他莫昔芬通过上调癌细胞中的 ALDH1A1 增强 ERα36 乳腺癌的干性并促进其转移。
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本文引用的文献

1
Tamoxifen enhances stemness and promotes metastasis of ERα36 breast cancer by upregulating ALDH1A1 in cancer cells.他莫昔芬通过上调癌细胞中的 ALDH1A1 增强 ERα36 乳腺癌的干性并促进其转移。
Cell Res. 2018 Mar;28(3):336-358. doi: 10.1038/cr.2018.15. Epub 2018 Feb 2.
2
Aromatase inhibitors versus tamoxifen in early breast cancer: patient-level meta-analysis of the randomised trials.芳香酶抑制剂与他莫昔芬治疗早期乳腺癌:随机试验的患者水平荟萃分析。
Lancet. 2015 Oct 3;386(10001):1341-1352. doi: 10.1016/S0140-6736(15)61074-1. Epub 2015 Jul 23.
3
Tamoxifen for prevention of breast cancer: extended long-term follow-up of the IBIS-I breast cancer prevention trial.他莫昔芬预防乳腺癌:IBIS-I 乳腺癌预防试验的长期随访。
Lancet Oncol. 2015 Jan;16(1):67-75. doi: 10.1016/S1470-2045(14)71171-4. Epub 2014 Dec 11.
4
ER-α36-mediated rapid estrogen signaling positively regulates ER-positive breast cancer stem/progenitor cells.雌激素受体α36介导的快速雌激素信号传导正向调节雌激素受体阳性乳腺癌干细胞/祖细胞。
PLoS One. 2014 Feb 18;9(2):e88034. doi: 10.1371/journal.pone.0088034. eCollection 2014.
5
Selective oestrogen receptor modulators in prevention of breast cancer: an updated meta-analysis of individual participant data.选择性雌激素受体调节剂在乳腺癌预防中的应用:一项个体参与者数据的更新荟萃分析。
Lancet. 2013 May 25;381(9880):1827-34. doi: 10.1016/S0140-6736(13)60140-3. Epub 2013 Apr 30.
6
Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: patient-level meta-analysis of randomised trials.乳腺癌激素受体及其他因素与辅助他莫昔芬疗效的相关性:随机试验的患者水平荟萃分析。
Lancet. 2011 Aug 27;378(9793):771-84. doi: 10.1016/S0140-6736(11)60993-8. Epub 2011 Jul 28.
7
Estrogen expands breast cancer stem-like cells through paracrine FGF/Tbx3 signaling.雌激素通过旁分泌 FGF/Tbx3 信号扩大乳腺癌干细胞样细胞。
Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21737-42. doi: 10.1073/pnas.1007863107. Epub 2010 Nov 22.
8
Expression of ER-{alpha}36, a novel variant of estrogen receptor {alpha}, and resistance to tamoxifen treatment in breast cancer.雌激素受体α的新型变体ER-α36的表达与乳腺癌对他莫昔芬治疗的耐药性
J Clin Oncol. 2009 Jul 20;27(21):3423-9. doi: 10.1200/JCO.2008.17.2254. Epub 2009 Jun 1.
9
ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome.醛脱氢酶1(ALDH1)是正常和恶性人乳腺干细胞的标志物,也是临床预后不良的预测指标。
Cell Stem Cell. 2007 Nov;1(5):555-67. doi: 10.1016/j.stem.2007.08.014.
10
Identification, cloning, and expression of human estrogen receptor-alpha36, a novel variant of human estrogen receptor-alpha66.人雌激素受体α66的新型变体——人雌激素受体α36的鉴定、克隆与表达
Biochem Biophys Res Commun. 2005 Nov 4;336(4):1023-7. doi: 10.1016/j.bbrc.2005.08.226.