Hashemi Hassan, Khabazkhoob Mehdi, Nabovati Payam, Yazdani Negareh, Ostadimoghaddam Hadi, Shiralivand Ehsan, Derakhshan Akbar, Yekta AbbasAli
Noor Research Center for Ophthalmic Epidemiology, Noor Eye Hospital, Tehran, Iran.
Department of Medical Surgical Nursing, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
J Curr Ophthalmol. 2017 Apr 2;30(1):35-41. doi: 10.1016/j.joco.2016.11.002. eCollection 2018 Mar.
To determine the normal range of intraocular pressure (IOP) in the young and its association with certain corneal parameters using a non-contact device.
Subjects were selected from students of Mashhad University of Medical Sciences through stratified sampling. All participants had visual acuity testing, corneal imaging, a comprehensive slit-lamp examination by an ophthalmologist, and IOP measurement using a non-contact air-puff tonometer.
Of the 1280 invitees, 1073 (83.8%) participated, and 1027 were eligible. Mean IOP was 16.38 mmHg [95% confidence interval (CI): 16.22-16.53] in the total sample, 16.14 mmHg (95% CI: 15.84-16.45) in men, and 16.48 mmHg (95% CI: 16.31-16.66) in women. There was a significant IOP difference between myopes and emmetropes ( = 0.031). Based on the multiple linear regression model, IOP associated directly with age and central corneal thickness (CCT), and inversely with corneal diameter, spherical equivalent (SE), and keratoconus. Based on standardized coefficients of the regression model, CCT and SE had the strongest association with IOP.
In the present study, we demonstrated the IOP distribution in a young population using a non-contact method. CCT and SE were strongly associated with IOP.
使用非接触式设备确定年轻人眼内压（IOP）的正常范围及其与某些角膜参数的关联。
通过分层抽样从马什哈德医科大学的学生中选取研究对象。所有参与者均进行了视力测试、角膜成像、眼科医生的全面裂隙灯检查以及使用非接触式气吹眼压计测量眼压。
在1280名受邀者中，1073人（83.8%）参与，1027人符合条件。总样本的平均眼压为16.38 mmHg [95%置信区间（CI）：16.22 - 16.53]，男性为16.14 mmHg（95% CI：15.84 - 16.45），女性为16.48 mmHg（95% CI：16.31 - 16.66）。近视者和正视者之间的眼压存在显著差异（P = 0.031）。基于多元线性回归模型，眼压与年龄和中央角膜厚度（CCT）直接相关，与角膜直径、等效球镜度（SE）和圆锥角膜呈负相关。根据回归模型的标准化系数，CCT和SE与眼压的关联最强。
在本研究中，我们使用非接触式方法展示了年轻人群的眼压分布。CCT和SE与眼压密切相关。
