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非肝硬化性门静脉高压症:影像学综述。

Non-cirrhotic portal hypertension: an imaging review.

机构信息

The Liver Unit, Cochin Gastroenterology Group, Department of Diagnostic and Interventional Radiology, Ernakulam Medical Centre, Kochi, India.

Department of Interventional Radiology, Institute of Liver and Biliary Sciences, D-1, Vasant Kunj, Off Abdul Gaffar Khan Marg, New Delhi, 110070, India.

出版信息

Abdom Radiol (NY). 2018 Aug;43(8):1991-2010. doi: 10.1007/s00261-018-1570-8.

Abstract

Non-cirrhotic portal hypertension (NCPH) comprises a group of diseases that are characterized by increased portal pressure in the absence of cirrhosis of the liver. It may arise as a result of either primary hepatic disease or the effects of systemic disorders on liver. The natural course of NCPH is largely indolent and benign with an overall better outcome than cirrhosis, as long as the complications of portal hypertension are properly managed and regular surveillance is carried out. However, due to the numerous and variable etiological factors and lack of standardized diagnostic criteria, this entity is under-recognized clinically as well as pathologically and often gets mislabeled as cryptogenic cirrhosis. Therefore, it is imperative for radiologists to be aware of the imaging features of various entities that constitute NCPH to facilitate early recognition of this disorder. The present review shall comprehensively discuss the role of imaging in the diagnosis of obliterative portal venopathy, which is a common and one of the most poorly understood disorders leading to NCPH. The other radiologically relevant entities will also be briefly appraised.

摘要

非肝硬化性门静脉高压症(NCPH)是一组以肝脏无肝硬化为特征的门静脉压力增高的疾病。它可能是由于原发性肝脏疾病或系统性疾病对肝脏的影响引起的。NCPH 的自然病程在很大程度上是惰性和良性的,只要门静脉高压的并发症得到适当的管理和定期监测,其总体预后要好于肝硬化。然而,由于病因众多且多变,缺乏标准化的诊断标准,这种疾病在临床上以及病理上都没有得到充分的认识,常常被误诊为隐源性肝硬化。因此,放射科医生必须了解构成 NCPH 的各种实体的影像学特征,以便及早识别这种疾病。本综述将全面讨论影像学在闭塞性门静脉病诊断中的作用,这是导致 NCPH 的一种常见且最不被理解的疾病之一。其他与放射学相关的实体也将简要评估。

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