Department of Chemistry, Merkert Chemistry Center , Boston College , Chestnut Hill , Massachusetts 02467 , United States.
Org Lett. 2018 Apr 6;20(7):1898-1901. doi: 10.1021/acs.orglett.8b00439. Epub 2018 Mar 22.
The convergent synthesis of candidate stereoisomers of the natural product arenolide was accomplished using recently developed catalytic boron-based reactions. Comparison of the spectral data for candidate structures with that reported for the authentic natural product revealed the likely stereostructure of the natural compound.
使用最近开发的催化硼基反应,完成了天然产物arenolide 的候选立体异构体的汇聚合成。候选结构的光谱数据与报道的天然产物的光谱数据进行比较,揭示了天然化合物可能的立体结构。