Department of Medicine/Endocrinology, Hospital of Southwest Jutland, Esbjerg, Denmark.
Department of Regional Health Research, University of Southern Denmark, Odense, Denmark.
Obesity (Silver Spring). 2018 May;26(5):828-837. doi: 10.1002/oby.22143. Epub 2018 Mar 22.
Bariatric surgery results in significant weight loss and reduces cardiovascular morbidity. However, a large variation in postsurgery weight loss is seen. Physical activity promotes weight loss in nonsurgically treated subjects with obesity. The aim of this study was to investigate the effects of 6 months of supervised physical training following Roux-en-Y gastric bypass surgery (RYGB) on body weight and cardiovascular risk markers.
Sixty participants eligible for RYGB were included. Six months post surgery, the participants were randomly assigned to either twice-weekly supervised physical training sessions in a fitness center (INT) or a control group (CON) for 26 weeks. Before surgery and 6, 12, and 24 months after surgery, the participants underwent an examination program that included anthropometric measurements, blood pressure, heart rate, blood samples, and an abdominal computed tomography scan.
RYGB significantly reduced body weight and improved cardiovascular risk markers (all P < 0.01). The supervised physical training intervention resulted in a 4.2-kg (CI: -0.2 to -8.3 kg) lower body weight in INT compared with CON at the study end (P = 0.042). The high-density lipoprotein concentration was significantly higher in INT than in CON at the termination of the intervention, but this was not maintained at the 24-months examination.
Physical training following RYGB improves weight loss and cardiovascular health.
减重手术可显著减轻体重并降低心血管发病率。然而，手术后的减重效果存在很大差异。身体活动可促进肥胖非手术治疗患者的体重减轻。本研究旨在探讨罗伊氏 Y 胃旁路手术后（RYGB） 6 个月监督体能训练对体重和心血管风险标志物的影响。
纳入了 60 名符合 RYGB 条件的参与者。手术后 6 个月，参与者被随机分配到健身中心进行每周两次的监督体能训练（INT）或对照组（CON），持续 26 周。在手术前和手术后 6、12 和 24 个月，参与者接受了一项检查计划，包括人体测量、血压、心率、血液样本和腹部计算机断层扫描。
RYGB 显著降低了体重并改善了心血管风险标志物（均 P<0.01）。与 CON 组相比，INT 组在研究结束时的体重降低了 4.2 公斤（CI：-0.2 至-8.3 公斤）（P=0.042）。干预结束时，INT 组的高密度脂蛋白浓度明显高于 CON 组，但在 24 个月检查时并未保持。
RYGB 后进行体能训练可改善体重减轻和心血管健康。
