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胃食管反流病手术后失败的处理

Management of failure after surgery for gastro-esophageal reflux disease.

作者信息

Gronnier C, Degrandi O, Collet D

机构信息

Unité de chirurgie oeso-gastric et endocrinienne, service de chirurgie digestive, centre Magellan, centre hospitalier universitaire de Bordeaux, avenue de Magellan, 33600 Pessac, France; Faculté de médecine de Bordeaux, 33000 Bordeaux, France.

Unité de chirurgie oeso-gastric et endocrinienne, service de chirurgie digestive, centre Magellan, centre hospitalier universitaire de Bordeaux, avenue de Magellan, 33600 Pessac, France; Faculté de médecine de Bordeaux, 33000 Bordeaux, France.

出版信息

J Visc Surg. 2018 Apr;155(2):127-139. doi: 10.1016/j.jviscsurg.2018.02.001. Epub 2018 Mar 19.

Abstract

Surgical treatment of gastro-esophageal reflux disease (ST-GERD) is well-codified and offers an alternative to long-term medical treatment with a better efficacy for short and long-term outcomes. However, failure of ST-GERD is observed in 2-20% of patients; management is challenging and not standardized. The aim of this study is to analyze the causes of failure and to provide a treatment algorithm. The clinical aspects of ST-GERD failure are variable including persistent reflux, dysphagia or permanent discomfort leading to an important degradation of the quality of life. A morphological and functional pre-therapeutic evaluation is necessary to: (i) determine whether the symptoms are due to recurrence of reflux or to an error in initial indication and (ii) to understand the cause of the failure. The most frequent causes of failure of ST-GERD include errors in the initial indication, which often only need medical treatment, and surgical technical errors, for which surgical redo surgery can be difficult. Multidisciplinary management is necessary in order to offer the best-adapted treatment.

摘要

胃食管反流病的外科治疗(ST-GERD)已得到充分规范,为长期药物治疗提供了一种替代方案,对短期和长期疗效均更佳。然而,2%-20%的患者会出现ST-GERD治疗失败的情况;管理具有挑战性且不规范。本研究的目的是分析失败原因并提供一种治疗算法。ST-GERD治疗失败的临床情况各不相同,包括持续性反流、吞咽困难或长期不适,导致生活质量严重下降。治疗前进行形态学和功能评估很有必要,以便:(i)确定症状是由于反流复发还是初始适应证错误,以及(ii)了解失败原因。ST-GERD治疗失败最常见的原因包括初始适应证错误(通常仅需药物治疗)和手术技术错误(对此进行再次手术可能很困难)。为了提供最适合的治疗,多学科管理是必要的。

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