Kuchibiro Tomokazu, Hirayama Katsuhisa, Houdai Katsuyuki, Nakamura Tatsuya, Ohnuma Kenichirou, Tomida Junko, Kawamura Yoshiaki
Department of Clinical Laboratory, Naga Municipal Hospital, 1282 Uchita, Kinokawa, Wakayama, 649-6414, Japan.
Department of Neurosurgery Medicine, Naga Municipal Hospital, 1282 Uchita, Kinokawa, Wakayama, 649-6414, Japan.
JMM Case Rep. 2018 Jan 10;5(1):e005135. doi: 10.1099/jmmcr.0.005135. eCollection 2018 Jan.
Species of the genus are opportunistic, usually saprophytic, glucose-non-fermenting, Gram-negative bacilli found in agricultural soil. infections are the least common infections and have low incidence.
Herein, we report the first case of sepsis with in Japan in a 67-year-old Japanese woman with a history of hyperlipidaemia, hypertension, diabetes, hypothyroidism and osteoporosis. She had undergone cerebrovascular treatment because she was diagnosed with a subarachnoid haemorrhage. The results of postoperative blood culture showed oxidase-positive, urease-positive, non-lactose-fermenting Gram-stain-negative rods. Using the Vitek2 system, the isolate was distinctly identified as . However, 16S rRNA gene sequencing showed 99.93 % similarity with the type strain of and 99.06 % similarity with the type strain of . Additional gene sequencing analysis using (97.2 %) and (96.2 %) also showed that the isolated strain is most closely related to . The patient was cured by treatment using intravenous meropenem (3 g/d) for 4 weeks and was discharged safely.
The definite source of sepsis was unknown. However, the possibility of having been infected through the catheter during the cerebrovascular operation was speculated.
该属菌种为机会致病菌,通常腐生,不发酵葡萄糖,革兰氏阴性杆菌,存在于农业土壤中。感染是最不常见的感染类型,发病率较低。
在此,我们报告日本首例67岁日本女性因感染导致败血症的病例,该女性有高脂血症、高血压、糖尿病、甲状腺功能减退和骨质疏松病史。她因诊断为蛛网膜下腔出血接受了脑血管治疗。术后血培养结果显示为氧化酶阳性、脲酶阳性、不发酵乳糖的革兰氏染色阴性杆菌。使用Vitek2系统,该分离株被明确鉴定为。然而,16S rRNA基因测序显示与的模式菌株相似度为99.93%,与的模式菌株相似度为99.06%。使用(97.2%)和(96.2%)进行的额外基因测序分析也表明,分离菌株与关系最为密切。患者通过静脉注射美罗培南(3g/d)治疗4周后治愈并安全出院。
败血症的确切来源不明。然而,推测可能是在脑血管手术期间通过导管感染。