Koch Karen
Wits University Donald Gordon Medical Centre, Johannesburg, South Africa.
South Afr J HIV Med. 2017 Aug 31;18(1):676. doi: 10.4102/sajhivmed.v18i1.676. eCollection 2017.
Photosensitive disorders are common, affecting up to 5% of HIV-positive patients. HIV itself induces photosensitivity but photoaggravated drug reactions, porphyria cutanea tarda and nutritional disorders such as pellagra are also more common in patients with HIV. In South Africa, actinic lichenoid leukomelanoderma of HIV is a unique photosensitive disorder which is associated with advanced HIV. It is important to be able to recognise these conditions and withdraw photosensitising medications wherever possible.
光敏性疾病很常见,影响多达5%的HIV阳性患者。HIV本身可诱发光敏性,但光加重性药物反应、迟发性皮肤卟啉症和营养障碍(如糙皮病)在HIV患者中也更常见。在南非,HIV相关性光化性苔藓样白黑变病是一种独特的光敏性疾病,与晚期HIV相关。能够识别这些情况并尽可能停用光敏药物很重要。