Department of Clinical Sciences, Neurology, Faculty of Medicine, Lund University, Lund, Sweden.
Department of Health Sciences, Mental Health, Activity and Participation (MAP), Lund University, Lund, Sweden.
Acta Neurol Scand. 2018 Jul;138(1):78-84. doi: 10.1111/ane.12929. Epub 2018 Mar 22.
Many countries have an aging population, and it is thus likely that Parkinson's disease (PD) will become an increasing health problem. It is important to ensure this group can use their resources in the best way possible, including remaining in the work market. This study aimed to investigate workforce participation and daily activities among patients with PD receiving device-aided therapy to provide new knowledge that may be used to inform decisions about these therapy options.
This was a retrospective, descriptive quantitative pilot study, including 67 patients with PD from 3 centers in Sweden and Denmark. Included patients were younger than 67 years at the time of introduction of device-aided therapy. Eligible patients were identified by the Swedish national Parkinson patient registry or by the treating neurologist. Quantitative interviews were made by telephone.
A majority of the patients could perform the same, or more, amount of activities approximately 5 years after the introduction of device-aided therapy. A small number of patients receiving deep brain stimulation (DBS) and levodopa-carbidopa intestinal gel (LCIG) were able to increase their work capacity within 1 year of initiating device-aided therapy and a remarkably high share could still work at the end-point of this study, approximately 15 years since the diagnosis of PD.
Device-aided therapy may sustain or increase daily activities and workforce participation in patients with PD who have not yet reached retirement age. There is need for prospective studies, both quantitative and qualitative, to confirm these results.
许多国家都面临人口老龄化问题，因此帕金森病（PD）可能会成为日益严重的健康问题。确保这一群体能够尽可能有效地利用他们的资源，包括留在工作市场中，这一点非常重要。本研究旨在调查接受设备辅助治疗的 PD 患者的劳动力参与和日常活动，以提供可能用于告知这些治疗选择的新信息。
这是一项回顾性、描述性的定量试点研究，纳入了来自瑞典和丹麦 3 个中心的 67 名 PD 患者。纳入研究的患者在接受设备辅助治疗时年龄小于 67 岁。符合条件的患者通过瑞典国家帕金森病患者登记处或主治神经科医生确定。通过电话进行了定量访谈。
大约 5 年后，大多数患者能够进行相同或更多数量的活动。少数接受深部脑刺激（DBS）和左旋多巴-卡比多巴肠凝胶（LCIG）治疗的患者能够在开始设备辅助治疗后的 1 年内增加其工作能力，并且在这项研究的终点处，仍有相当大比例的患者可以工作，大约在 PD 诊断后的 15 年。
设备辅助治疗可能维持或增加尚未达到退休年龄的 PD 患者的日常活动和劳动力参与。需要进行前瞻性研究，包括定量和定性研究，以证实这些结果。
