在常规临床实践中于急诊科就诊的静脉血栓栓塞症患者的治疗方法：EDITH 研究。

Therapeutic approach for patients with venous thromboembolism attended in emergency departments during routine clinical practice: the EDITH study.

机构信息

Emergency Department, Hospital Clínico San Carlos, IdISSC, Madrid, Spain.

Emergency Department, Hospital Reina Sofía, Murcia, Spain.

出版信息

J Comp Eff Res. 2018 Apr;7(4):319-330. doi: 10.2217/cer-2017-0061. Epub 2018 Mar 23.

DOI:10.2217/cer-2017-0061

PMID:29570366

Abstract

AIM

To analyze treatment at discharge/follow-up of patients diagnosed with venous thromboembolism (VTE) in the emergency department (ED).

MATERIALS & METHODS: Ambispective study (50 Spanish centers) of consecutive patients (October-December 2014) with VTE diagnosed in ED.

RESULTS

VTE was diagnosed in 775 patients (295 pulmonary embolism [PE] without deep vein thrombosis [DVT], 389 DVT without PE and 91 PE + DVT); 95.5% received anticoagulants (90.7% low-molecular-weight heparin [LMWH], 4% LMWH + vitamin K antagonists and <1% direct oral anticoagulants). Overall, 23.3% were discharged from ED and 74.5% hospitalized (98.6% with PE and 50.4% with DVT). After discharge/90/180 days, 43.6/21.0/13.5% were taking LMWH, with similar rates in nononcologic patients.

CONCLUSION

There is a poor adherence to international guidelines in management of VTE patients in Spain.

摘要

目的

分析在急诊科（ED）诊断为静脉血栓栓塞症（VTE）的患者出院/随访时的治疗情况。

材料与方法

对 2014 年 10 月至 12 月在 50 家西班牙中心连续就诊的 VTE 患者（295 例无深静脉血栓形成 [DVT] 的肺栓塞 [PE]、389 例无 PE 的 DVT 和 91 例 PE+DVT）进行前瞻性研究。

结果

共诊断出 775 例 VTE 患者（95.5%接受抗凝治疗[90.7%低分子肝素 [LMWH]、4% LMWH+维生素 K 拮抗剂和 <1%直接口服抗凝剂]）。总体而言，23.3%从 ED 出院，74.5%住院（98.6%为 PE，50.4%为 DVT）。出院后 90 天和 180 天，分别有 43.6%、21.0%和 13.5%的患者继续使用 LMWH，非肿瘤患者的使用率相似。