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患者的术前背景会导致腹腔镜辅助保留幽门胃切除术后出现胃潴留。

Patients' preoperative background causes gastric stasis after laparoscopy-assisted pylorus-preserving gastrectomy.

作者信息

Nishizawa Nobuyuki, Hosoda Kei, Moriya Hiromitsu, Mieno Hiroaki, Ema Akira, Ushiku Hideki, Ishii Satoru, Tanaka Toshimichi, Washio Marie, Yokoi Keigo, Harada Hiroki, Watanabe Masahiko, Yamashita Keishi

机构信息

Department of Surgery, Kitasato University School of Medicine, Sagamihara, Japan.

Division of Advanced Surgical Oncology, Research and Development Center for New Medical Frontiers, Kitasato University School of Medicine, Sagamihara, Japan.

出版信息

Asian J Endosc Surg. 2018 Nov;11(4):337-345. doi: 10.1111/ases.12477. Epub 2018 Mar 23.

Abstract

INTRODUCTION

Despite technical improvements in laparoscopic gastrectomy, gastric stasis is still a serious problem in laparoscopy-assisted pylorus-preserving gastrectomy (LAPPG). The aim of this study was to investigate the factors that might cause gastric stasis in LAPPG.

METHODS

From April 2004 through November 2012, 85 patients with cT1N0 middle-third gastric cancer who underwent LAPPG at Kitasato University Hospital; these patients were included in the present study. Infra-pyloric vein (IPV)-preserving LAPPG was performed in 41 patients. We compared the rate of gastric stasis in the IPV-preserving and the IPV-non-preserving groups, and analyzed the clinicopathological factors that might have caused gastric stasis.

RESULTS

We did not demonstrate that preservation of the IPV could prevent gastric stasis in the early and late postoperative periods. Symptoms of gastric stasis were most frequently recognized 1 year after surgery. A significantly higher proportion of preoperative ASA class 2 patients had gastric stasis than did not (80.0% [12/15] vs 48.6% [34/70], P=0.02). Among the ASA class 2 patients, a significantly greater proportion of those with depressed activities of daily living than those with normal activities of daily living had gastric stasis (66.7% [4/6] vs 20.0% [8/40], P = 0.015).

CONCLUSIONS

The clinical significance of the IPV preservation in LAPPG could not be demonstrated. LAPPG should be performed for ASA class 1 patients or those with maintained preoperative activities of daily living.

摘要

引言

尽管腹腔镜胃切除术技术有所改进,但胃潴留仍是腹腔镜辅助保留幽门胃切除术(LAPPG)中的一个严重问题。本研究旨在探讨LAPPG中可能导致胃潴留的因素。

方法

2004年4月至2012年11月,85例cT1N0期胃中部癌患者在北里大学医院接受了LAPPG;这些患者被纳入本研究。41例患者接受了保留幽门下静脉(IPV)的LAPPG。我们比较了保留IPV组和未保留IPV组的胃潴留发生率,并分析了可能导致胃潴留的临床病理因素。

结果

我们并未证明保留IPV可预防术后早期和晚期的胃潴留。胃潴留症状最常在术后1年出现。术前ASA分级为2级的患者发生胃潴留的比例显著高于未发生胃潴留的患者(80.0%[12/15]对48.6%[34/70],P=0.02)。在ASA分级为2级的患者中,日常生活活动能力低下的患者发生胃潴留的比例显著高于日常生活活动能力正常的患者(66.7%[4/6]对20.0%[8/40],P=0.015)。

结论

LAPPG中保留IPV的临床意义未能得到证实。LAPPG应仅用于ASA分级为1级的患者或术前日常生活活动能力未受影响的患者。

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