Josephson M A, Nademanee K, Intarachot V, Lewis H, Singh B N
J Am Coll Cardiol. 1987 Sep;10(3):499-503. doi: 10.1016/s0735-1097(87)80190-0.
Twenty-four hour Holter ambulatory electrocardiographic recordings were obtained before and after successful coronary angioplasty in 36 patients. Twenty-five patients had one vessel, 10 had two vessel and 1 had three vessel coronary artery disease. Holter monitor-detected myocardial ischemia, defined as ST segment depression or elevation greater than or equal to 1 mm, was present in 10 patients (28%). These 10 patients had a total of 39 ischemic episodes of 3 to 144 minutes' duration, with a total cumulative duration of 398 minutes. None of the 10 had Holter monitor-detected ischemia after successful angioplasty (p less than 0.01). Treadmill exercise duration increased by 29% after coronary angioplasty (p less than 0.01), and peak exercise heart rate-systolic blood pressure product increased by 27% (p less than 0.01). Thus, Holter monitor-detected myocardial ischemia is a relatively uncommon finding in patients with predominant single vessel coronary artery disease undergoing coronary angioplasty. When such ischemia is present, it is eliminated by successful coronary angioplasty.
对36例患者在成功进行冠状动脉血管成形术前和术后进行了24小时动态心电图记录。25例患者为单支血管病变，10例为双支血管病变，1例为三支血管病变。动态心电图监测发现10例患者（28%）存在心肌缺血，定义为ST段压低或抬高≥1mm。这10例患者共有39次缺血发作，持续时间为3至144分钟，总累计时长为398分钟。10例患者在成功进行血管成形术后均未发现动态心电图监测到的缺血（p<0.01）。冠状动脉血管成形术后平板运动持续时间增加了29%（p<0.01），运动高峰心率-收缩压乘积增加了27%（p<0.01）。因此，在接受冠状动脉血管成形术的以单支血管病变为主的患者中，动态心电图监测到的心肌缺血是相对少见的发现。当出现这种缺血时，成功的冠状动脉血管成形术可将其消除。
