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In vitro prediction of drug-induced cholestatic liver injury: a challenge for the toxicologist.

作者信息

Vinken Mathieu

机构信息

Department of In Vitro Toxicology and Dermato-Cosmetology, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090, Brussels, Belgium.

出版信息

Arch Toxicol. 2018 May;92(5):1909-1912. doi: 10.1007/s00204-018-2201-4. Epub 2018 Mar 24.

Abstract
摘要

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本文引用的文献

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An Update on Adverse Outcome Pathways Leading to Liver Injury.
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Adverse outcome pathways: opportunities, limitations and open questions.
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Adverse outcome pathways: a concise introduction for toxicologists.
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The role of Kupffer cells in hepatic diseases.
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Evaluation of transcriptomic signature as a valuable tool to study drug-induced cholestasis in primary human hepatocytes.
Arch Toxicol. 2017 Aug;91(8):2879-2893. doi: 10.1007/s00204-017-1930-0. Epub 2017 Feb 10.
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Integrative "-Omics" Analysis in Primary Human Hepatocytes Unravels Persistent Mechanisms of Cyclosporine A-Induced Cholestasis.
Chem Res Toxicol. 2016 Dec 19;29(12):2164-2174. doi: 10.1021/acs.chemrestox.6b00337. Epub 2016 Dec 2.

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