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用于皮肤恶性肿瘤的莫氏显微外科手术:儿科年龄组适应症的重点综述

Mohs micrographic surgery for cutaneous malignancies: A focus review of its indications in pediatric age groups.

作者信息

Le Stephanie T, Kamal Heba Y, Khachemoune Amor

机构信息

Drexel/Hahnemann University Hospital, Philadelphia, PA, USA.

Hamad Medical Corporation, Doha, Qatar.

出版信息

Pediatr Dermatol. 2018 Jul;35(4):434-440. doi: 10.1111/pde.13460. Epub 2018 Mar 25.

DOI:10.1111/pde.13460
PMID:29575263
Abstract

Mohs micrographic surgery (MMS) is a highly specialized technique that has been successful in the treatment of a variety of skin tumors. The technique can be performed as an outpatient procedure and encompasses surgical excision and intraoperative assessment of tumor margins in one setting by the same physician. The process ensures precise margin control with maximal preservation of healthy tissues. Mohs micrographic surgery has been practiced worldwide, including in the United States, Europe (United Kingdom, Germany, Spain, Netherlands, Switzerland), and Australia. Although it is commonly performed in adults with greater success, it has been discussed less frequently in children. In this article, we describe several cutaneous tumors in children and the role of Mohs micrographic surgery in their management. A PubMed search was conducted to review the most common cutaneous tumors in children treated using Mohs micrographic surgery. In this review, we discuss indications for Mohs micrographic surgery and pertinent studies examining success rates in children. Mohs micrographic surgery has been used to treat several tumors in children and offers the advantage of high cure rates and tissue conservation. This report emphasizes the benefits of Mohs micrographic surgery in children and highlights several cutaneous tumors for which it has been used to treat successfully.

摘要

莫氏显微外科手术(MMS)是一种高度专业化的技术,已成功应用于多种皮肤肿瘤的治疗。该技术可作为门诊手术进行,由同一位医生在同一环境中完成手术切除和术中肿瘤边缘评估。这一过程确保了精确的边缘控制,同时最大程度地保留健康组织。莫氏显微外科手术已在全球范围内开展,包括美国、欧洲(英国、德国、西班牙、荷兰、瑞士)和澳大利亚。虽然它在成人中应用更为普遍且成功率更高,但在儿童中的讨论相对较少。在本文中,我们描述了几种儿童皮肤肿瘤以及莫氏显微外科手术在其治疗中的作用。我们通过PubMed搜索来回顾使用莫氏显微外科手术治疗的儿童中最常见的皮肤肿瘤。在本综述中,我们讨论了莫氏显微外科手术的适应症以及相关研究中儿童的成功率。莫氏显微外科手术已用于治疗儿童的多种肿瘤,并具有治愈率高和组织保留的优势。本报告强调了莫氏显微外科手术在儿童中的益处,并突出了几种已成功应用该手术治疗的皮肤肿瘤。

相似文献

1
Mohs micrographic surgery for cutaneous malignancies: A focus review of its indications in pediatric age groups.用于皮肤恶性肿瘤的莫氏显微外科手术:儿科年龄组适应症的重点综述
Pediatr Dermatol. 2018 Jul;35(4):434-440. doi: 10.1111/pde.13460. Epub 2018 Mar 25.
2
Mohs Micrographic Surgery for the Management of Cutaneous Malignancies.用于治疗皮肤恶性肿瘤的莫氏显微外科手术
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Mohs Micrographic Surgery.莫氏显微外科手术
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The use of Mohs micrographic surgery (MMS) for melanoma in situ (MIS) of the trunk and proximal extremities.在躯干和近端肢体原位黑色素瘤(MIS)中使用Mohs 显微外科手术(MMS)。
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Outcomes of Melanoma In Situ Treated With Mohs Micrographic Surgery Compared With Wide Local Excision.莫氏显微外科手术与广泛局部切除治疗原位黑色素瘤的疗效比较
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Dermatofibrosarcoma protuberans (DFSP): growth characteristics based on tumor modeling and a review of cases treated with Mohs micrographic surgery.隆突性皮肤纤维肉瘤(DFSP):基于肿瘤建模的生长特征及Mohs显微外科手术治疗病例回顾
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Cutaneous head and neck melanoma treated with Mohs micrographic surgery.采用莫氏显微外科手术治疗的头颈部皮肤黑色素瘤。
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[Recurrent acral lentigous melanoma successfully treated with Mohs' micrographic surgery. Case report and review of the literature].[复发性肢端雀斑样痣黑色素瘤经莫氏显微外科手术成功治疗。病例报告及文献综述]
Orv Hetil. 2009 Jun 7;150(23):1071-82. doi: 10.1556/OH.2009.28612.
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Mohs micrographic surgery technique.Mohs 显微外科手术技术。
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Dermatofibrosarcoma protuberans treated with Mohs micrographic surgery: cure rates and surgical margins.用莫氏显微外科手术治疗隆突性皮肤纤维肉瘤:治愈率和手术切缘
Dermatol Surg. 1996 Jun;22(6):530-4.

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AXIN2 and SNAIL expression predict the risk of recurrence in cutaneous squamous cell carcinoma after Mohs micrographic surgery.AXIN2和SNAIL的表达可预测莫氏显微外科手术后皮肤鳞状细胞癌的复发风险。
Oncol Lett. 2020 Mar;19(3):2133-2140. doi: 10.3892/ol.2020.11324. Epub 2020 Jan 21.