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Enhanced terminal room disinfection and acquisition and infection caused by multidrug-resistant organisms and Clostridium difficile (the Benefits of Enhanced Terminal Room Disinfection study): a cluster-randomised, multicentre, crossover study.强化终末病房消毒与多重耐药菌及艰难梭菌所致获得性感染（强化终末病房消毒的益处研究）：一项整群随机、多中心、交叉研究。
Lancet. 2017 Feb 25;389(10071):805-814. doi: 10.1016/S0140-6736(16)31588-4. Epub 2017 Jan 17.
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Expert Consensus on Metrics to Assess the Impact of Patient-Level Antimicrobial Stewardship Interventions in Acute-Care Settings.评估急性护理环境中患者层面抗菌药物管理干预措施影响的指标专家共识
Clin Infect Dis. 2017 Feb 1;64(3):377-383. doi: 10.1093/cid/ciw787. Epub 2016 Dec 7.
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Antibiotic Use in Small Community Hospitals.小型社区医院的抗生素使用情况。
Clin Infect Dis. 2016 Nov 15;63(10):1273-1280. doi: 10.1093/cid/ciw588. Epub 2016 Sep 30.
4
Core elements of hospital antibiotic stewardship programs from the Centers for Disease Control and Prevention.美国疾病控制与预防中心医院抗生素管理计划的核心要素。
Clin Infect Dis. 2014 Oct 15;59 Suppl 3(Suppl 3):S97-100. doi: 10.1093/cid/ciu542.
5
Antimicrobial use metrics and benchmarking to improve stewardship outcomes: methodology, opportunities, and challenges.抗菌药物使用指标与基准设定以改善管理成效：方法、机遇与挑战
Infect Dis Clin North Am. 2014 Jun;28(2):195-214. doi: 10.1016/j.idc.2014.01.006.
6
Use of a structured panel process to define quality metrics for antimicrobial stewardship programs.采用结构化小组流程来定义抗菌药物管理项目的质量指标。
Infect Control Hosp Epidemiol. 2012 May;33(5):500-6. doi: 10.1086/665324. Epub 2012 Mar 20.
7
Measurement of adult antibacterial drug use in 130 US hospitals: comparison of defined daily dose and days of therapy.美国130家医院成人抗菌药物使用情况的测量：限定日剂量与治疗天数的比较。
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分母在估计抗菌药物使用中的重要性：日用药数与患者日的比较。

Denominator Matters in Estimating Antimicrobial Use: A Comparison of Days Present and Patient Days.

机构信息

1Duke Center for Antimicrobial Stewardship and Infection Prevention,Duke University,Durham,North Carolina.

2Department of Biostatistics,Duke University,Durham,North Carolina.

出版信息

Infect Control Hosp Epidemiol. 2018 May;39(5):612-615. doi: 10.1017/ice.2018.54. Epub 2018 Mar 26.

DOI:10.1017/ice.2018.54
PMID:29576019
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6503660/
Abstract

Patient days and days present were compared to directly measured person time to quantify how choice of different denominator metrics may affect antimicrobial use rates. Overall, days present were approximately one-third higher than patient days. This difference varied among hospitals and units and was influenced by short length of stay.Infect Control Hosp Epidemiol 2018;39:612-615.

摘要

将实际患者日和报告患者日进行对比，以直接衡量患者人时来量化不同分母指标的选择如何影响抗菌药物使用率。总体而言，报告患者日比实际患者日高约三分之一。这种差异在不同医院和科室之间有所不同，受到住院时间短的影响。感染控制与医院流行病学 2018；39:612-615.