地衣芽孢杆菌 BL-010 的全基因组序列。

Complete genome sequence of Bacillus licheniformis BL-010.

机构信息

Institute of Chemistry and Biological Engineering, Department of Biological Technology, University of Science and Technology Beijing, Beijing 100083, People's Republic of China.

出版信息

Microb Pathog. 2018 May;118:199-201. doi: 10.1016/j.micpath.2018.03.037. Epub 2018 Mar 22.

DOI:10.1016/j.micpath.2018.03.037

PMID:29578060

Abstract

The biodegradation of Aflatoxin B (AFB) is an industry of increasing importance. Bacillus licheniformis BL-010 was isolated from the aflatoxin contaminated corn feed storage, and was shown to degrade AFB efficiently. Here we present the complete genome sequence of BL-010, the genome comprises 4,287,714 bp in a circular chromosome with a GC content of 46.12% and contains genes encoding AFB degrading enzymes. The genome sequence displayed that this strain contains genes involved in production of laccase, aromatic ring-opening dioxygenase which could detoxify AFB. Complete genome sequence of the strain BL-010 can further provide the genomic basis for the biotechnological application of strain BL-010 as an effective way to degrade AFB.

摘要

黄曲霉毒素 B（AFB）的生物降解是一个日益重要的产业。地衣芽孢杆菌 BL-010 是从受黄曲霉毒素污染的玉米饲料储存中分离出来的，被证明能有效地降解 AFB。在这里，我们呈现了 BL-010 的完整基因组序列，该基因组由一个 4,287,714 bp 的环状染色体组成，GC 含量为 46.12%，包含编码 AFB 降解酶的基因。基因组序列显示，该菌株含有参与产生漆酶、芳香环开环双加氧酶的基因，这些基因可以解毒 AFB。菌株 BL-010 的完整基因组序列可以进一步为菌株 BL-010 的生物技术应用提供基因组基础，作为有效降解 AFB 的方法。