Community Engagement and Outreach, University of California, Davis Comprehensive Cancer Center, Sacramento, California.
Division of Hematology and Oncology, University of California, Davis School of Medicine, Sacramento, California.
Cancer. 2018 Apr 1;124 Suppl 7(Suppl 7):1614-1621. doi: 10.1002/cncr.31168.
Biospecimens from racially diverse groups are needed to advance cancer research. The Asian American Cancer Education Study was developed to increase the number and proportion of blood biospecimen donations from Asian Americans for cancer research.
The authors' targeted approach included 2 types of community engagement, in-reach (within institution to Asian American patients with cancer) and outreach (external to institution to the general Asian American community). Participants received in-language biospecimen education followed by the opportunity to donate blood biospecimens. Outreach participants donated through our community biospecimen blood drives, and in-reach participants consented to donating an extra tube of blood during their routine blood draws as a patient. Donated blood biospecimens were spun down to serum and plasma to be stored in a biorepository or were sent to the laboratory to test for cancer-related risk factors.
Three hundred eighty-eight Asian Americans donated 1127 blood biospecimens for cancer research. Four hundred twenty tubes of plasma and serum are currently being stored at the cancer center's biorepository, 39 tubes have been used for cancer genomic research, and 668 tubes were used to characterize cancer-related risk factors.
Building upon the past decade of the National Cancer Institute-funded Asian American Network for Cancer Awareness, Research, and Training's foundation of trust and service among Asian Americans, researchers were able to leverage relationships not only to introduce the idea of biospecimen contribution to the community but to also exceed expectations with regard to the quantity of blood biospecimens collected from Asian Americans. Cancer 2018;124:1614-21. © 2018 American Cancer Society.
为推进癌症研究，需要有来自不同种族群体的生物标本。美国亚裔癌症教育研究旨在增加亚裔美国人的血液生物标本数量和比例，用于癌症研究。
作者采用了两种类型的社区参与方式，即内部参与（面向机构内的亚裔癌症患者）和外部参与（面向机构外的一般亚裔社区）。参与者接受了生物标本教育，随后有机会捐献血液生物标本。外部参与的参与者通过我们的社区生物标本采血活动进行捐献，内部参与的参与者则在作为患者接受常规采血时同意额外捐献一管血液。捐献的血液生物标本被离心分离出血清和血浆，储存在生物库中，或送往实验室检测与癌症相关的风险因素。
388 名亚裔美国人共捐献了 1127 份血液生物标本用于癌症研究。目前，420 管血浆和血清储存在癌症中心的生物库中，39 管已用于癌症基因组研究，668 管用于分析与癌症相关的风险因素。
在过去十年里，美国国立卫生研究院资助的亚裔美国人癌症意识、研究和培训网络建立了亚裔美国人之间的信任和服务基础，研究人员不仅利用这些关系向社区介绍了生物标本捐献的想法，而且还超出了预期，从亚裔美国人那里收集了大量的血液生物标本。癌症 2018;124:1614-21。©2018 美国癌症协会。
