高疫苗覆盖率环境下 b 型流感嗜血杆菌引起的侵袭性疾病的临床特征。
Clinical Characterization of Invasive Disease Caused by Haemophilus influenzae Serotype b in a High Vaccination Coverage Setting.
机构信息
Centre for Infectious Disease Control Netherlands (CIb), National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.
European Programme for Intervention Epidemiology Training, European Centre for Disease Prevention and Control, Stockholm, Sweden.
出版信息
J Pediatric Infect Dis Soc. 2019 Jul 1;8(3):261-264. doi: 10.1093/jpids/piy020.
This national study characterized invasive Haemophilus influenzae serotype b infections. Vaccinated (n = 41) and nonvaccinated (n = 10) cases were similar regarding presentation as meningitis (68.8% vs 90.0%; P = .25), predisposing factors (29.3% vs 20.0%; P = .76), admission to intensive care unit or death (22.0% vs 10.0%; P = 1.00), or sequelae (21.6% vs 10.0%; P = .81). Haemophilus influenzae serotype b occurred in vaccinated, healthy children with comparable disease course.
本项全国性研究对侵袭性流感嗜血杆菌 b 型感染进行了特征描述。接种疫苗组（n=41）和未接种疫苗组（n=10）在表现为脑膜炎方面（68.8% vs 90.0%；P=.25）、潜在因素（29.3% vs 20.0%；P=.76）、入住重症监护病房或死亡（22.0% vs 10.0%；P= 1.00）或后遗症（21.6% vs 10.0%；P=.81）方面相似。接种疫苗的健康儿童也会发生流感嗜血杆菌 b 型侵袭性疾病，且疾病进程相当。
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