Palmeri R, Papalia E, Lazzara S, Belnome N A, Gorgone S, Calbo E, Melita P
Università degli Studi di Messina, Istituto di Chirurgia Generale.
Chir Ital. 1987 Apr;39(2):185-92.
After discussing the mechanism of action of antioestrogens and medroxy-progesterone-acetate, the authors report on their experience with the sequential use of these two hormones in a group of patients with advanced cancer of the breast. After illustrating the results of their study, the authors conclude by stressing that the sequential use of these drugs appears to improve the quality of life of the patients with a significant increase in rates of complete or partial remission of the neoplastic disease.
在讨论了抗雌激素药物和醋酸甲羟孕酮的作用机制后,作者报告了他们在一组晚期乳腺癌患者中序贯使用这两种激素的经验。在阐述了研究结果后,作者强调,序贯使用这些药物似乎能提高患者的生活质量,肿瘤疾病的完全或部分缓解率显著提高。