Division of Inpatient Medicine, Department of Pediatrics, University of Utah School of Medicine, Primary Children's Hospital, Salt Lake City.
Division of General Pediatrics, University of Utah School of Medicine, Salt Lake City.
JAMA Pediatr. 2018 May 1;172(5):482-486. doi: 10.1001/jamapediatrics.2017.5752.
Medical overuse has historically focused on adult health care, but interest in how children are affected by medical overuse is increasing. This review examines important research articles published in 2016 that address pediatric overuse.
A structured search of PubMed and a manual review of the tables of contents of 10 journals identified 169 articles related to pediatric overuse published in 2016, from which 8 were selected based on the quality of methods and potential harm to patients in terms of prevalence and magnitude. Articles were categorized by overtreatment, overmedicalization, and overdiagnosis. Findings included evidence of overtreatment with commercial rehydration solution, antidepressants, and parenteral nutrition; overmedicalization with planned early deliveries, immobilization of ankle injuries, and use of hydrolyzed infant formula; and evidence of overdiagnosis of hypoxemia among children recovering from bronchiolitis.
The articles were of high quality, with most based on randomized clinical trials. The potential harms associated with pediatric overuse were significant, including increased risk of infection, developmental disability, and suicidality.
医学过度治疗历来集中于成人保健,但人们对儿童受医学过度治疗影响的兴趣日益增加。本综述考察了 2016 年发表的、探讨儿科过度治疗的重要研究文章。
通过对 PubMed 进行有结构检索,并对 10 种期刊的目录进行人工审查,共确定了 2016 年发表的 169 篇与儿科过度治疗相关的文章,其中 8 篇文章是根据方法的质量和对患者的潜在危害(包括流行程度和严重程度)选择的。文章按过度治疗、过度医疗化和过度诊断进行分类。研究结果包括商业补液、抗抑郁药和肠外营养过度治疗的证据;计划性早产、踝关节损伤固定、水解婴儿配方奶粉过度使用的过度医疗化证据;以及毛细支气管炎恢复期儿童低氧血症过度诊断的证据。
这些文章质量很高,大多数基于随机临床试验。儿科过度治疗相关的潜在危害是显著的,包括感染风险增加、发育障碍和自杀风险。