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2018 年过度医疗更新。

2018 Update on Medical Overuse.

机构信息

Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore.

Department of Hospital Epidemiology, Veterans Affairs Maryland Health Care System, Baltimore.

出版信息

JAMA Intern Med. 2019 Feb 1;179(2):240-246. doi: 10.1001/jamainternmed.2018.5748.

Abstract

IMPORTANCE

Overuse of medical care is a well-recognized problem in health care, associated with patient harm and costs. We sought to identify and highlight original research articles published in 2017 that are most relevant to understanding medical overuse.

OBSERVATIONS

A structured review of English-language articles published in 2017 was performed, coupled with examination of tables of contents of high-impact journals to identify articles related to medical overuse in adult care. Manuscripts were appraised for their quality, clinical relevance, and impact. A total of 1446 articles were identified, 910 of which addressed medical overuse. Of these, 111 articles were deemed to be the most relevant based on originality, methodologic quality, and scope. The 10 most influential articles were selected by author consensus. Findings included that unnecessary electrocardiograms are common (performed in 22% of patients at low risk) and can lead to a cascade of services, lipid monitoring rarely affects care, patients who were overdiagnosed with cancer experienced anxiety and criticism about not seeking treatment, calcium and vitamin D supplementation does not reduce hip fracture (relative risk, 1.09; 95% CI, 0.85-1.39), and pregabalin does not improve symptoms of sciatica but frequently has adverse effects (40% of patients experienced dizziness). Antipsychotic medications increased the severity of delirium in patients receiving hospice care and were associated with an increased risk of death (hazard ratio, 1.7; P = .003), and robotic-assisted radical nephrectomy was without benefits by being slower and more costly than laparoscopic surgery. High-sensitivity troponin testing often yielded false-positive results, as 16% of patients with positive troponin results in a US hospital had a myocardial infarction. One-third of patients who received a diagnosis of asthma had no evidence of asthma. Restructuring the electronic health record was able to reduce unnecessary testing (from 31.3 to 13.9 low-value tests performed per 100 patient visits).

CONCLUSIONS AND RELEVANCE

Many current practices were found to represent overuse, with no benefit and potential harms. Other services were used inappropriately. Reviewing these findings and extrapolating to their patients will enable health care professionals to improve the care they provide.

摘要

重要性

医疗保健中超用医疗的现象是一个众所周知的问题,它与患者伤害和费用有关。我们试图确定并强调 2017 年发表的与理解医疗过度使用最相关的原创研究文章。

观察结果

对 2017 年发表的英文文章进行了结构化审查,并对高影响力期刊的目录进行了检查,以确定与成人保健中医疗过度使用相关的文章。对这些文章进行了评估,以确定其质量、临床相关性和影响力。共确定了 1446 篇文章,其中 910 篇涉及医疗过度使用。其中,根据创新性、方法学质量和范围,有 111 篇文章被认为是最相关的。作者一致认为,10 篇最有影响力的文章被选中。研究结果表明,不必要的心电图检查很常见(低危患者中有 22%接受了检查),并可能导致一系列服务;血脂监测很少影响治疗;被过度诊断为癌症的患者经历了焦虑和对不接受治疗的批评;钙和维生素 D 补充剂不能减少髋部骨折(相对风险,1.09;95%置信区间,0.85-1.39);普瑞巴林不能改善坐骨神经痛症状,但经常有不良反应(40%的患者出现头晕)。抗精神病药物会加重接受临终关怀的患者的谵妄严重程度,并增加死亡风险(风险比,1.7;P=0.003),机器人辅助根治性肾切除术比腹腔镜手术慢且成本更高,因此没有益处。高敏肌钙蛋白检测常产生假阳性结果,因为美国医院中 16%肌钙蛋白检测结果阳性的患者发生心肌梗死。三分之一被诊断为哮喘的患者没有哮喘的证据。重构电子健康记录能够减少不必要的检查(每 100 次就诊中,低价值检查从 31.3 次减少到 13.9 次)。

结论和相关性

许多目前的做法被发现是过度使用的,没有好处,反而存在潜在危害。其他服务也被不恰当地使用。审查这些发现并推断到他们的患者,将使医疗保健专业人员能够改善他们提供的护理。

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