紫花糙叶黄耆变种拉氏黄耆中的一种新环阿尔廷烷皂苷——拉氏皂苷

Laceioside, a new cycloartane saponin from Astragalus tephrosioides Boiss. var. lacei (Ali) Kirchoff.

作者信息

Ahmad Viqar Uddin, Mohammad Faryal Vali, Tareen Rasool Bakhsh

机构信息

a H.E.J Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi , Karachi , Pakistan.

b Department of Botany, Baluchistan University , Quetta , Pakistan.

出版信息

Nat Prod Res. 2019 Feb;33(3):393-399. doi: 10.1080/14786419.2018.1455042. Epub 2018 Mar 27.

DOI:10.1080/14786419.2018.1455042

PMID:29587529

Abstract

Phytochemical investigation of the aerial parts of Astragalus tephrosioides Boiss. var. lacei (Ali) Kirchoff. (Family Fabaceae) resulted in the isolation of a new cycloartane glycoside laceioside (1). The structure of the previously undescribed compound 1 was established as 16β-acetyloxy-3- O-β-d-glucopyranosyloxy-cycloartan-11α,24ξ, 25-triol. The structure elucidation of compound 1 was based primarily on 1D and 2D-NMR techniques including H and CNMR spectra, DEPT and by 2D COSY, HSQC and HMBC experiments.

摘要

对苦豆子状黄芪（Astragalus tephrosioides Boiss. var. lacei (Ali) Kirchoff.）（豆科）地上部分进行植物化学研究，分离得到一种新的环阿尔廷烷糖苷——拉塞苷（1）。前所未有的化合物1的结构确定为16β - 乙酰氧基 - 3 - O - β - D - 吡喃葡萄糖氧基 - 环阿尔廷 - 11α,24ξ,25 - 三醇。化合物1的结构解析主要基于一维和二维核磁共振技术，包括氢谱和碳谱、DEPT谱以及二维COSY、HSQC和HMBC实验。