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Low conversion rate of QuantiFERON-TB Gold screening tests in patients treated with tumor necrosis factor inhibitors: A retrospective cohort study identifying an important practice gap.

作者信息

Chung Jina, Aronson Adam B, Srikantha Rithu, Vogelgesang Scott A, Wanat Karolyn A

机构信息

Department of Dermatology, University of Iowa Carver College of Medicine, Iowa City, Iowa.

Department of Dermatology, University of Iowa Carver College of Medicine, Iowa City, Iowa.

出版信息

J Am Acad Dermatol. 2018 Jul;79(1):169-171. doi: 10.1016/j.jaad.2018.03.025. Epub 2018 Mar 26.

DOI:10.1016/j.jaad.2018.03.025
PMID:29588247
Abstract
摘要

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Low conversion rate of QuantiFERON-TB Gold screening tests in patients treated with tumor necrosis factor inhibitors: A retrospective cohort study identifying an important practice gap.接受肿瘤坏死因子抑制剂治疗的患者中，QuantiFERON-TB Gold筛查试验的转化率较低：一项回顾性队列研究揭示了一个重要的实践差距。
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2
Frequent conversion of tuberculosis screening tests during anti-tumour necrosis factor therapy in patients with rheumatic diseases.在风湿性疾病患者接受肿瘤坏死因子拮抗剂治疗期间，结核筛查试验频繁转换。
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How frequently do tuberculosis screening tests convert in inflammatory bowel disease patients on anti-tumour necrosis factor-alpha? A pilot study.在接受抗肿瘤坏死因子-α治疗的炎症性肠病患者中，结核筛查试验的转化频率有多高？一项初步研究。
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Interferon-γ release assay versus tuberculin skin test prior to treatment with golimumab, a human anti-tumor necrosis factor antibody, in patients with rheumatoid arthritis, psoriatic arthritis, or ankylosing spondylitis.在类风湿关节炎、银屑病关节炎或强直性脊柱炎患者中，使用人抗肿瘤坏死因子抗体戈利木单抗治疗前，γ干扰素释放试验与结核菌素皮肤试验的比较。
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Comparison of Quantiferon-TB Gold versus tuberculin skin test for tuberculosis screening in inflammatory bowel disease patients.比较定量干扰素-TB 黄金与结核菌素皮肤试验在炎症性肠病患者中的结核病筛查。
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Comment on: Use of the QuantiFERON TB Gold test as part of a screening programme in patients with RA under consideration for treatment with anti-TNF-alpha agents: the Newcastle (UK) experience.关于以下内容的评论：将结核感染T细胞检测（QuantiFERON TB Gold test）用作考虑使用抗TNF-α药物治疗的类风湿关节炎患者筛查计划的一部分：英国纽卡斯尔的经验
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Influence of replacing tuberculin skin test with ex vivo interferon γ release assays on decision to administer prophylactic antituberculosis antibiotics before anti-TNF therapy.用体外干扰素 γ 释放试验替代结核菌素皮肤试验对接受抗 TNF 治疗前预防性使用抗结核抗生素的决策的影响。
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TST, QuantiFERON-TB Gold test and T-SPOT.TB test for detecting latent tuberculosis infection in patients with rheumatic disease prior to anti-TNF therapy.在抗TNF治疗前，采用结核菌素皮肤试验（TST）、结核感染T细胞检测（QuantiFERON-TB Gold试验）和T-SPOT.TB试验检测风湿病患者的潜伏性结核感染。
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引用本文的文献

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Low rate of seroconversion analyzing QuantiFERON TB-gold testing in patients with psoriasis and hidradenitis suppurativa taking biologic therapy at an academic center in New York City.在纽约市一家学术中心，对接受生物治疗的银屑病和化脓性汗腺炎患者进行QuantiFERON TB-金检测时血清转化率较低。
JAAD Int. 2024 May 10;16:183-185. doi: 10.1016/j.jdin.2024.04.004. eCollection 2024 Sep.
2
Conversion Rate of Tuberculosis Screening Tests among Dermatology Patients Treated with Tumor Necrosis Factor Inhibitors.接受肿瘤坏死因子抑制剂治疗的皮肤科患者中结核病筛查试验的转化率
Indian J Dermatol. 2022 Jan-Feb;67(1):1-4. doi: 10.4103/ijd.ijd_201_21.
3
Conversion and Reversion Rates of Tuberculosis Screening Assays in Patients With Rheumatic Diseases and Negative Baseline Screening Under Long-Term Biologic Treatment.
长期生物治疗下风湿病患者及基线筛查阴性患者的结核病筛查检测的转化率和逆转率
Pathog Immun. 2020 Feb 26;5(1):34-51. doi: 10.20411/pai.v5i1.349. eCollection 2020.
4
The seroconversion rate of QuantiFERON-TB Gold In-Tube test in psoriatic patients receiving secukinumab and ixekizumab, the anti-interleukin-17A monoclonal antibodies.接受司库奇尤单抗和依奇珠单抗（抗白细胞介素-17A 单克隆抗体）治疗的银屑病患者中，QuantiFERON-TB Gold In-Tube 检测的血清转化率。
PLoS One. 2019 Dec 27;14(12):e0225112. doi: 10.1371/journal.pone.0225112. eCollection 2019.
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The prevalence of latent tuberculosis in dermatology patients on immunosuppressant therapy in New Orleans, Louisiana: A retrospective record review.路易斯安那州新奥尔良市接受免疫抑制治疗的皮肤科患者中潜伏性结核病的患病率：一项回顾性记录审查。
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