Koganti Sudheer, Kotecha Tushar, Rakhit Roby D
Barts, Heart Centre.
University College London Institute of Cardiovascular Science.
Interv Cardiol. 2016 May;11(1):11-16. doi: 10.15420/icr.2016:6:1.
Intracoronary imaging has the capability of accurately measuring vessel and stenosis dimensions, assessing vessel integrity, characterising lesion morphology and guiding optimal percutaneous coronary intervention (PCI). Coronary angiography used to detect and assess coronary stenosis severity has limitations. The 2D nature of fluoroscopic imaging provides lumen profile only and the assessment of coronary stenosis by visual estimation is subjective and prone to error. Performing PCI based on coronary angiography alone is inadequate for determining key metrics of the vessel such as dimension, extent of disease, and plaque distribution and composition. The advent of intracoronary imaging has offset the limitations of angiography and has shifted the paradigm to allow a detailed, objective appreciation of disease extent and morphology, vessel diameter, stent size and deployment and healing after PCI. It has become an essential tool in complex PCI, including rotational atherectomy, in follow-up of novel drug-eluting stent platforms and understanding the pathophysiology of stent failure after PCI (e.g. following stent thrombosis or in-stent restenosis). In this review we look at the two currently available and commonly used intracoronary imaging tools - intravascular ultrasound and optical coherence tomography - and the merits of each.
冠状动脉内成像能够精确测量血管和狭窄的尺寸,评估血管完整性,描述病变形态,并指导最佳经皮冠状动脉介入治疗(PCI)。用于检测和评估冠状动脉狭窄严重程度的冠状动脉造影存在局限性。荧光透视成像的二维特性仅提供管腔轮廓,通过视觉估计评估冠状动脉狭窄具有主观性且容易出错。仅基于冠状动脉造影进行PCI不足以确定血管的关键指标,如尺寸、病变范围以及斑块分布和成分。冠状动脉内成像的出现弥补了血管造影的局限性,并转变了模式,以便能够详细、客观地了解疾病范围和形态、血管直径、支架尺寸以及PCI后的植入和愈合情况。它已成为复杂PCI(包括旋磨术)、新型药物洗脱支架平台随访以及理解PCI后支架失败(如支架血栓形成或支架内再狭窄后)病理生理学的重要工具。在本综述中,我们将探讨两种目前可用且常用的冠状动脉内成像工具——血管内超声和光学相干断层扫描——以及它们各自的优点。