van Ditzhuijzen Nienke S, Ligthart Jurgen Mr, Bruining Nico, Regar Evelyn, van Beusekom Heleen Mm
Department of Cardiology, Division of Experimental Cardiology.
Cardiovascular Research School COEUR, Erasmus University Medical Centre, Rotterdam, The Netherlands.
Interv Cardiol. 2013 Mar;8(1):23-35. doi: 10.15420/icr.2013.8.1.23.
Various fully bioresorbable stents (BRS) have been recently developed, allowing for temporary scaffolding of the vessel wall. The potentially unique advantage of BRS to temporary scaffold the vessel could reduce the risk of adverse clinical outcomes caused by acute vessel geometry changes, late malapposition, jailed side branches or inflexibility of permanent stents. The design of BRS is, however, not similar for all stents, resulting in differences in degradation and behaviour. To assess the performance of BRS, the effect of degradation and behaviour on the vessel wall should be accurately evaluated. Intracoronary imaging techniques such as intravascular ultrasound (IVUS), optical coherence tomography (OCT) and near-infrared spectroscopy (NIRS) allow for detailed longitudinal evaluation of the stent and the vessel wall and might therefore aid in improving design and behaviour of BRS.
最近已开发出各种完全可生物吸收支架（BRS），可对血管壁进行临时支撑。BRS对血管进行临时支撑这一潜在的独特优势可降低因急性血管几何形状改变、晚期贴壁不良、分支血管受压或永久性支架缺乏柔韧性而导致不良临床结局的风险。然而，并非所有BRS的设计都相似，这导致了降解和性能方面的差异。为了评估BRS的性能，应准确评估降解和性能对血管壁的影响。血管内超声（IVUS）、光学相干断层扫描（OCT）和近红外光谱（NIRS）等冠状动脉内成像技术可对支架和血管壁进行详细的纵向评估，因此可能有助于改进BRS的设计和性能。
