Grubb Kendra J, Nazif Tamim, Williams Mathew R, George Isaac
Division of Cardiothoracic Surgery, College of Physicians and Surgeons.
Division of Cardiology, Columbia University Medical Center, New York, US.
Interv Cardiol. 2013 Aug;8(2):127-130. doi: 10.15420/icr.2013.8.2.127.
Concomitant coronary artery disease (CAD) and valvular heart disease is an increasingly common problem in the ageing population. Hybrid procedures combine surgical and transcatheter approaches to facilitate minimally invasive surgery or to transform a single high-risk open surgery into two less risky procedures. In ideal circumstances, this strategy may decrease the surgical risk in elderly, high-risk and reoperative surgical candidates, while improving patient comfort, convenience and cost-effectiveness. Hybrid procedures can be performed in a staged fashion or as a 'one-stop' procedure in a hybrid operating suite. Increasing evidence supports the safety and short-term efficacy of hybrid valve repair or replacement and coronary revascularisation procedures. Nevertheless, important questions remain, including the optimal timing of the individual procedures and the optimal antiplatelet therapy after percutaneous coronary intervention. With ongoing advances in procedural techniques and anticoagulation strategies, as well as the accumulation of long-term outcomes data, hybrid approaches to concomitant CAD and valvular heart disease will likely become increasingly common.
冠状动脉疾病(CAD)与心脏瓣膜病并存是老龄化人口中日益常见的问题。杂交手术结合了外科手术和经导管方法,以促进微创手术或将单一的高风险开放手术转变为两个风险较低的手术。在理想情况下,这种策略可能会降低老年、高风险和再次手术患者的手术风险,同时提高患者的舒适度、便利性和成本效益。杂交手术可以分阶段进行,也可以在杂交手术室中作为“一站式”手术进行。越来越多的证据支持杂交瓣膜修复或置换以及冠状动脉血运重建手术的安全性和短期疗效。然而,重要问题仍然存在,包括各个手术的最佳时机以及经皮冠状动脉介入治疗后的最佳抗血小板治疗。随着手术技术和抗凝策略的不断进步,以及长期结果数据的积累,针对并存CAD和心脏瓣膜病的杂交方法可能会越来越普遍。