Stratmann H, Aker U T, Vandormael M G, Ischinger T, Wiens R, Kennedy H L
Department of Cardiology, St. Louis Veterans Administration Medical Center, Missouri.
Angiology. 1987 Sep;38(9):663-71. doi: 10.1177/000331978703800903.
Right atrial pacing (RAP) was used to immediately assess improvement in threshold for myocardial ischemia in 23 patients undergoing angiographically successful percutaneous transluminal coronary angioplasty (PTCA). Multiple coronary lesions were present in 19 patients, and 15 had incomplete revascularization. All patients had RAP done immediately before and after completion of all dilatations, and in 13 patients pre- and post-PTCA exercise treadmill tests (ETT) were also performed. Angina occurred in 16 (70%) patients during pre-PTCA RAP, but in only 4 (17%) after PTCA (p less than .05). The electrocardiogram was positive for ischemia (horizontal or downsloping ST depression greater than or equal to 1 mm) in 18 patients (78%) during pre-PTCA RAP. However, 13 patients (57%) continued to have an ischemic response during post-PTCA RAP (not significant-NS). In 4 patients with multiple coronary lesions who had sequential pacing studies after PTCA of each lesion, the maximum degree of ST depression decreased by 1 mm or more after each dilatation in 3 patients but remained greater than or equal to 1 mm in all. In the 13 patients undergoing both RAP and ETT, angina developed in 7 during pre-PTCA RAP and in 2 after PTCA (p less than .05), compared with 8 and 3 (p less than .05) during pre- and post-PTCA ETT, respectively. Ischemic ST depression occurred in 9 patients during pre-PTCA RAP and in 6 after PTCA (NS), and in 8 and 6 (NS) during pre- and post-PTCA ETT, respectively. Concordance between the two tests was good.(ABSTRACT TRUNCATED AT 250 WORDS)
对23例经血管造影证实经皮腔内冠状动脉成形术(PTCA)成功的患者,采用右心房起搏(RAP)立即评估心肌缺血阈值的改善情况。19例患者存在多处冠状动脉病变,15例患者血运重建不完全。所有患者在完成所有扩张术前、后均立即进行RAP,13例患者在PTCA术前、后还进行了运动平板试验(ETT)。PTCA术前RAP期间,16例(70%)患者出现心绞痛,但PTCA术后仅4例(17%)出现心绞痛(p<0.05)。PTCA术前RAP期间,18例患者(78%)心电图缺血阳性(水平或下斜型ST段压低≥1mm)。然而,PTCA术后RAP期间,13例患者(57%)仍有缺血反应(无显著性差异-NS)。4例有多支冠状动脉病变的患者在对每个病变进行PTCA后进行序贯起搏研究,3例患者每次扩张后ST段压低的最大程度降低1mm或更多,但所有患者仍≥1mm。在13例同时进行RAP和ETT的患者中,PTCA术前RAP期间7例患者出现心绞痛,PTCA术后2例出现心绞痛(p<0.05),而PTCA术前、后ETT期间分别为8例和3例(p<0.05)。PTCA术前RAP期间9例患者出现缺血性ST段压低,PTCA术后6例出现(无显著性差异),PTCA术前、后ETT期间分别为8例和6例(无显著性差异)。两种检查结果的一致性良好。(摘要截短为250字)