El Khoury Raymonda, Warren Mitchell, Ali Saba, Pirkle James L
Department of Internal Medicine, Section on Nephrology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Case Rep Nephrol Dial. 2017 Dec 22;7(3):172-177. doi: 10.1159/000485500. eCollection 2017 Sep-Dec.
This case describes an obese adult male peritoneal dialysis patient who presented with a pruritic follicular rash. Nutrient deficiency was not suspected initially in this case because there was no history of protein-calorie malnutrition, but the patient reported a diet devoid of fruits and vegetables and had not been taking his dialysis vitamin as prescribed. Skin biopsy showed follicular hyperkeratosis with fragmented hair shafts and corkscrew hairs consistent with scurvy. After supplementation with ascorbic acid 500 mg twice daily for 2 weeks, the rash resolved completely. Dialysis patients are at increased risk for vitamin C deficiency due to indiscriminant clearance of the nutrient with dialysis, but scurvy is rarely seen.
本病例描述了一名肥胖成年男性腹膜透析患者,该患者出现了瘙痒性毛囊皮疹。最初未怀疑该病例存在营养缺乏,因为没有蛋白质 - 热量营养不良史,但患者报告其饮食中缺乏水果和蔬菜,且未按医嘱服用透析维生素。皮肤活检显示毛囊角化过度,伴有毛发干断裂和螺旋状毛发,符合坏血病表现。在每天两次补充500毫克抗坏血酸,持续2周后,皮疹完全消退。由于透析会无差别清除营养素,透析患者维生素C缺乏风险增加,但坏血病很少见。