Camerlingo M, Bottacchi E, Gambaro P, D'Alessandro G, Carenini L, Mamoli A
Neurology and Neurophysiopathology Service, Regional Hospital, Aosta, Italy.
Funct Neurol. 1987 Apr-Jun;2(2):227-30.
Parasympathetic function in 7 Huntington's chorea patients with a duration of the disease ranging from 1 to 20 years, was evaluated by studying R-R intervals during quiet and deep breathing and Valsalva manoeuvre. All 7 patients were free of neuropathy, orthostatic hypotension, heart or lung disease and had had no medication for at least 15 days prior to hospitalization. Seven normal subjects served as controls. On the whole, the responses of the Huntington's chorea patients were not significantly different from those of the controls. Abnormal responses to all the tests were received in only one patient and a low R-R variability during deep breathing in the youngest patients. Unlike other Central Nervous System degenerative disorders, in Huntington's disease parasympathetic autonomy seems to be sufficiently preserved.
通过研究7例病程为1至20年的亨廷顿舞蹈症患者在安静及深呼吸时的R-R间期以及瓦尔萨尔瓦动作，对其副交感神经功能进行了评估。所有7例患者均无神经病变、直立性低血压、心肺疾病，且在住院前至少15天未服用任何药物。7名正常受试者作为对照。总体而言，亨廷顿舞蹈症患者的反应与对照组无显著差异。仅1例患者对所有测试的反应异常，最年轻的患者在深呼吸时R-R变异性较低。与其他中枢神经系统退行性疾病不同，在亨廷顿病中副交感神经自主性似乎得到了充分保留。
