核医学中使用的核素“剂量校准器”设置的最新情况。
An update on 'dose calibrator' settings for nuclides used in nuclear medicine.
作者信息
Bergeron Denis E, Cessna Jeffrey T
机构信息
Physical Measurement Laboratory, National Institute of Standards and Technology, Gaithersburg, Maryland, USA.
出版信息
Nucl Med Commun. 2018 Jun;39(6):500-504. doi: 10.1097/MNM.0000000000000833.
BACKGROUND
Most clinical measurements of radioactivity, whether for therapeutic or imaging nuclides, rely on commercial re-entrant ionization chambers ('dose calibrators'). The National Institute of Standards and Technology (NIST) maintains a battery of representative calibrators and works to link calibration settings ('dial settings') to primary radioactivity standards. Here, we provide a summary of NIST-determined dial settings for 22 radionuclides.
METHODS
We collected previously published dial settings and determined some new ones using either the calibration curve method or the dialing-in approach.
RESULTS
The dial settings with their uncertainties are collected in a comprehensive table.
CONCLUSION
In general, current manufacturer-provided calibration settings give activities that agree with National Institute of Standards and Technology standards to within a few percent.
背景
大多数放射性的临床测量，无论是针对治疗性还是成像性核素，都依赖于商业用的再入式电离室（“剂量校准仪”）。美国国家标准与技术研究院（NIST）保存了一系列有代表性的校准仪，并致力于将校准设置（“刻度盘设置”）与基本放射性标准联系起来。在此，我们总结了NIST确定的22种放射性核素的刻度盘设置。
方法
我们收集了先前发表的刻度盘设置，并使用校准曲线法或拨入法确定了一些新的设置。
结果
带有不确定度的刻度盘设置汇总在一张综合表格中。
结论
一般来说，当前制造商提供的校准设置所给出的活度与美国国家标准与技术研究院的标准相符，误差在百分之几以内。
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